Evidence map›Paper›PMID 40454148›Full record

ReviewFrontiers in medicine2025

Association between hypoglycemia and poor clinical outcomes in hospitalized non-diabetic patients with liver cirrhosis:- a narrative review.

Rohit Govindarajan, Jiancong Chen, Kunsong Zhang, Wenjie Hu, Dan Xu, Ming Kuang

Abstract readReview
In one paragraph

Review in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rohit Govindarajan *General Practice Research and International Collaboration, Faculty of Health Sciences, Curtin Medical School, Curtin University, Perth, WA, Australia.
Jiancong Chen *Department of Hepatobiliary Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Kunsong ZhangDepartment of Hepatobiliary Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Wenjie HuDepartment of Hepatobiliary Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Dan XuGeneral Practice Research and International Collaboration, Faculty of Health Sciences, Curtin Medical School, Curtin University, Perth, WA, Australia.
Ming KuangDepartment of Hepatobiliary Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypoglycemia is rarely highlighted as a complication that requires close monitoring in patients with chronic liver disease, despite substantial evidence of its occurrence in cirrhotic patients. This narrative review aims to evaluate whether hypoglycemia in liver cirrhosis patients, irrespective of diabetes status, exacerbates complications and warrants targeted management strategies. Our analysis reveals that hypoglycemia is prevalent in cirrhotic patients and is associated with increased mortality and complications compared to normoglycemic patients. Although literature in this topic is limited, our review suggests that early identification of high-risk liver disease patients and the implementation of novel, clinically relevant strategies to minimize hypoglycemia may improve clinical outcomes and health-related quality of life as well as reduce morbidity and mortality. Further research will be required to validate thesel strategies.

Indexed as

chronic liver diseasecirrhosisclinical guidelinescomplicationshypoglycemia

Identifiers

PMID40454148
PMCPMC12122455

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.