Evidence map›Paper›PMID 40454105›Full record

SynthesisGlobal heart2025

Medication Adherence and Contributing Factors in Patients with Heart Failure Within the Middle East: A Systematic Review.

Mohammed Alfaqeeh, Ramez Abdullah, Neily Zakiyah, Auliya A Suwantika, Maarten J Postma, Fita Rahmawati, Anna Wahyuni Widayanti, Baharudin Ibrahim

Abstract readSystematic Review
In one paragraph

Synthesis in Global heart, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mohammed AlfaqeehDepartment of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Bandung, Indonesia.ORCID 0000-0002-4079-869X
Ramez AbdullahDepartment of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta, Indonesia.ORCID 0009-0006-1371-3466
Neily ZakiyahDepartment of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Bandung, Indonesia.ORCID 0000-0002-9630-5567
Auliya A SuwantikaDepartment of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Bandung, Indonesia.ORCID 0000-0001-8671-2065
Maarten J PostmaCenter for Health Technology Assessment, Universitas Padjadjaran, Bandung, Indonesia.ORCID 0000-0002-6306-3653
Fita RahmawatiDepartment of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta, Indonesia.ORCID 0000-0001-6698-5621
Anna Wahyuni WidayantiDepartment of Pharmaceutics, Faculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta, Indonesia.ORCID 0000-0002-7723-5911
Baharudin IbrahimDepartment of Clinical Pharmacy and Pharmacy Practices, Faculty of Pharmacy, Universiti Malaya, Kuala Lumpur, Malaysia.ORCID 0000-0001-8534-2517

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Medication adherence among heart failure (HF) patients in the Middle East remains a critical, under-explored issue. This systematic review examines medication adherence rates and their influencing factors in this region. A search of PubMed, Scopus, and Google Scholar identified 12 studies published between 2013 and 2023, revealing an average non-adherence rate of 60%. Influential factors include socioeconomic status, education, psychiatric conditions, and medication-related issues. Significant gaps in research methodologies and reporting were noted. The review highlights the impact of socio-economic determinants on adherence and calls for more robust research and targeted interventions to address these barriers. Improving patient education and healthcare provider communication are crucial to enhancing adherence rates. These findings underscore the importance of addressing regional challenges through tailored approaches and suggest further studies are needed to develop effective strategies for improving adherence among HF patients in the Middle East.

Indexed as

Heart FailureMedication AdherenceHumansMiddle EastHeart failureMedication adherencenon-adherence factorsQuality assessment

Identifiers

PMID40454105
PMCPMC12124249

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.