Evidence map›Paper›PMID 40454074›Full record

ArticleACS omega2025

Dissection of an Anaerobic Fungal Cellulosomal Endoglucanase: Impact of the Dockerin Module on Activity, Thermostability, and Flexibility.

Viviane Brito Andrade, Robson Tramontina, Dnane Vieira Almeida, Geizecler Tomazetto, Viviam M da Silva, Frank Gabel, Yolanda M B Marcello, Ana Ligia Scott, Fabio Marcio Squina, Wanius Garcia

Abstract read
In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Discovery and functional characterization of endoglucanases fromApplied and environmental microbiology · 2026
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Viviane Brito AndradeCentro de Ciências Naturais e Humanas (CCNH), Universidade Federal do ABC (UFABC), Avenida dos Estados 5001, Bairro Bangu, Santo Andre, SP CEP 09280-560, Brazil.
Robson TramontinaDepartment of Biochemistry and Tissue Biology, Institute of Biology, Universidade Estadual de Campinas (UNICAMP), Rua Monteiro Lobato 255, Campinas, SP CEP 13083-970, Brazil.ORCID https://orcid.org/0000-0001-6265-733X
Dnane Vieira AlmeidaCentro de Ciências Naturais e Humanas (CCNH), Universidade Federal do ABC (UFABC), Avenida dos Estados 5001, Bairro Bangu, Santo Andre, SP CEP 09280-560, Brazil.
Geizecler TomazettoSchool of Medicine, Department of Pediatrics, University of Pittsburgh, 4401 Penn Avenue, Pittsburgh, Pennsylvania 15224-1334, United States.ORCID https://orcid.org/0000-0001-9530-2746
Viviam M da SilvaInstitut de Biologie Structurale (IBS), CEA, CNRS, UGA, 71 Avenue des Martyrs, CS 10090,Grenoble 38000, France.
Frank GabelInstitut de Biologie Structurale (IBS), CEA, CNRS, UGA, 71 Avenue des Martyrs, CS 10090,Grenoble 38000, France.
Yolanda M B MarcelloCentro de Matemática, Computação e Cognição (CMCC), Universidade Federal do ABC (UFABC), Avenida dos Estados 5001, Bairro Bangu, Santo Andre, SP CEP 09280-560, Brazil.
Ana Ligia ScottCentro de Matemática, Computação e Cognição (CMCC), Universidade Federal do ABC (UFABC), Avenida dos Estados 5001, Bairro Bangu, Santo Andre, SP CEP 09280-560, Brazil.
Fabio Marcio SquinaLaboratório de Ciências Moleculares, Universidade de Sorocaba (UNISO), Rodovia Raposo Tavares, km 92,5, Sorocaba, SP CEP 18023-000, Brazil.
Wanius GarciaCentro de Ciências Naturais e Humanas (CCNH), Universidade Federal do ABC (UFABC), Avenida dos Estados 5001, Bairro Bangu, Santo Andre, SP CEP 09280-560, Brazil.ORCID https://orcid.org/0000-0003-3712-3488

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cellulosomal cellulases possess an extra noncatalytic module denominated dockerin, which interacts with the scaffolding via cohesion modules to organize the enzymes within the cellulosome. Given the lack of previously solved experimental atomic structures for modular anaerobic fungal cellulases containing dockerin modules, here we employed structural modeling, molecular dynamics simulations, small-angle X-ray scattering, and biochemical analyses to gain new insights into the structure and function of cellulosomal endoglucanase from the anaerobic gut fungus Piromyces finnis (

Identifiers

PMID40454074
PMCPMC12120621

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.