Evidence map›Paper›PMID 40454052›Full record

ArticleACS omega2025

Nicotianin-I: A Tobacco Floral Nectar Peptide with Anticandidal Activity.

João M M Neto, Tawanny K B Aguiar, Mariana F Oliveira, Queilane L S G Chaves, Dário R A L Mourão, Viviane O Silva, Maria T V Nascimento, Rômulo F Carneiro, Rafael X Martins, Davi F Farias and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

João M M NetoDepartment of Biochemistry and Molecular Biology, Federal University of Ceará, Pici Campus, Fortaleza-Ceará CEP 60440-554, Brazil.
Tawanny K B AguiarDepartment of Biochemistry and Molecular Biology, Federal University of Ceará, Pici Campus, Fortaleza-Ceará CEP 60440-554, Brazil.
Mariana F OliveiraDepartment of Biochemistry and Molecular Biology, Federal University of Ceará, Pici Campus, Fortaleza-Ceará CEP 60440-554, Brazil.
Queilane L S G ChavesDepartment of Biochemistry and Molecular Biology, Federal University of Ceará, Pici Campus, Fortaleza-Ceará CEP 60440-554, Brazil.
Dário R A L MourãoDepartment of Biochemistry and Molecular Biology, Federal University of Ceará, Pici Campus, Fortaleza-Ceará CEP 60440-554, Brazil.
Viviane O SilvaDepartment of Biochemistry and Molecular Biology, Federal University of Ceará, Pici Campus, Fortaleza-Ceará CEP 60440-554, Brazil.
Maria T V NascimentoDepartment of Biology, Federal University of Ceará, Pici Campus, Fortaleza-Ceará CEP 60440-554, Brazil.
Rômulo F CarneiroDepartment of Fishing Engineering, Federal University of Ceará, Pici Campus, Fortaleza-Ceará CEP 60440-554, Brazil.ORCID https://orcid.org/0000-0003-0024-2512
Rafael X MartinsLaboratory for Risk Assessment of Novel Technologies (LabRisk), Department of Molecular Biology, Federal University of Paraiba, Campus I, João Pessoa CEP 58051-900, Brazil.
Davi F FariasLaboratory for Risk Assessment of Novel Technologies (LabRisk), Department of Molecular Biology, Federal University of Paraiba, Campus I, João Pessoa CEP 58051-900, Brazil.
Brandon F SousaDepartment of Biochemistry and Molecular Biology, Federal University of Ceará, Pici Campus, Fortaleza-Ceará CEP 60440-554, Brazil.
Jeanlex S SousaBiological Physics Laboratory, Physics Department, Federal University of Ceará, Pici Campus, Fortaleza-Ceará CEP 60440-554, Brazil.
Márcio V RamosDepartment of Biochemistry and Molecular Biology, Federal University of Ceará, Pici Campus, Fortaleza-Ceará CEP 60440-554, Brazil.
Cleverson D T FreitasDepartment of Biochemistry and Molecular Biology, Federal University of Ceará, Pici Campus, Fortaleza-Ceará CEP 60440-554, Brazil.ORCID https://orcid.org/0000-0002-2203-1575

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multidrug-resistant microorganisms are major threats to society, leading to the necessity of alternative molecules to fight them back. Antimicrobial peptides (AMPs), especially those derived from plants, have become relevant for multiple reasons. Therefore, this study evaluated six peptides identified in the floral nectar of ornamental tobacco for their effectiveness against four clinically relevant yeast species (Candida albicans, Candida krusei, Candida parapsilosis, and Candida tropicalis). Pep6 (KHYSCTRHGYCLACYKRWF) was the only one that showed activity against all yeast species, with IC

Identifiers

PMID40454052
PMCPMC12120630

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.