Polyhydroquinoline Amides: Comprehensive Study on Synthesis, In Vivo Biological Activities, and Computational Analysis Including Molecular Docking, DFT, and ADMET.

Zainab, Aftab Alam, Irfan Amir Khan, Ahmed A Elhenawy, Abdul Jabbar Shah, Mumtaz Ali, Manzoor Ahmad, Haitao Yu

Abstract read

In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

ZainabCollege of Chemistry and Materials Science, Hebei Normal University, Shijiazhuang 050024, China.

Aftab AlamDepartment of Chemistry, University of Malakand, Chakdara, Dir (L) , Khyber Pakhtunkhwa 18800, Pakistan.ORCID https://orcid.org/0000-0003-0475-2376

Irfan Amir KhanCardiovascular Research Group, Department of Pharmacy, COMSATS University Islamabad, Abbottabad Campus, Abbottabad , Khyber Pakhtunkhwa 22060, Pakistan.

Ahmed A ElhenawyChemistry Department, Faculty of Science, Al-Azhar University, Nasr City , Cairo 11884, Egypt.ORCID https://orcid.org/0000-0003-2893-0376

Abdul Jabbar ShahCardiovascular Research Group, Department of Pharmacy, COMSATS University Islamabad, Abbottabad Campus, Abbottabad , Khyber Pakhtunkhwa 22060, Pakistan.

Mumtaz AliDepartment of Chemistry, University of Malakand, Chakdara, Dir (L) , Khyber Pakhtunkhwa 18800, Pakistan.ORCID https://orcid.org/0000-0001-7573-7953

Manzoor AhmadDepartment of Chemistry, University of Malakand, Chakdara, Dir (L) , Khyber Pakhtunkhwa 18800, Pakistan.ORCID https://orcid.org/0000-0001-9736-5900

Haitao YuCollege of Chemistry and Materials Science, Hebei Normal University, Shijiazhuang 050024, China.ORCID https://orcid.org/0000-0003-3116-0288

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Twenty-four new amide derivatives of polyhydroquinoline

Identifiers

PMID40454032

DOI10.1021/acsomega.4c10647

PMCPMC12120658

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC-ND

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.