Evidence map›Paper›PMID 40453978›Full record

ArticleAlzheimer's & dementia (New York, N. Y.)

Yuzhuo Wang, Xiaoxi Ma, Haoze Cen, Jie Wang, Jie Wu, Ding Ding, Yiqin Xiao, Qianhua Zhao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Alzheimer's & dementia (New York, N. Y.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Alzheimer's & dementia (New York, N. Y.)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yuzhuo WangInstitute and Department of Neurology Huashan Hospital Fudan University Shanghai China.
Xiaoxi MaInstitute and Department of Neurology Huashan Hospital Fudan University Shanghai China.
Haoze CenSchool of Statistics and Data Science, Shanghai University of Finance and Economics Shanghai China.
Jie WangInstitute and Department of Neurology Huashan Hospital Fudan University Shanghai China.
Jie WuInstitute and Department of Neurology Huashan Hospital Fudan University Shanghai China.
Ding DingInstitute and Department of Neurology Huashan Hospital Fudan University Shanghai China.
Yiqin XiaoDepartment of Ophthalmology Huashan Hospital Fudan University Shanghai China.
Qianhua ZhaoInstitute and Department of Neurology Huashan Hospital Fudan University Shanghai China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionEmerging evidence links retinal nerve fiber layer (RNFL) thinning to cognitive impairment, while the apolipoprotein E (

methodsThis study included 35,433 participants from the UK Biobank. Generalized linear models and Jonckheere-Terpstra tests assessed the association between

resultsAmong 35,433 participants, 392 (1.11%) developed dementia over a median follow-up of 12.49 years (interquartile range: 12.39 to 12.64). DISCUSSION: Our findings resolve a controversy by showing that while Highlights: The association between

Indexed as

Alzheimer's diseaseapolipoprotein E ε4dementiamarkerretinal nerve fiber layer

Identifiers

PMID40453978
PMCPMC12122260

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.