ArticleJournal of inflammation research2025
Muscone Ameliorates High-Altitude Hypoxia Gastrointestinal Stress via Modulation of Lactobacillus Murinus and Mitochondrial Metabolism.
Article in Journal of inflammation research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Article
- Gut bacteriome alterations during high altitude exposure: a comprehensive analysis of different species.Frontiers in microbiology · 2026Review
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: This study is to investigate the previously unexamined mechanism through which muscone alleviates acute high-altitude gastrointestinal stress. Specifically, it focuses on the modulation of gut microbiota, emphasizing its role in promoting the abundance of Patients and Methods: A high-altitude hypoxia model mouse treated with muscone was established to assess routine blood indices, inflammatory factors, and inflammatory cell counts. Additionally, alterations in intestinal flora were analyzed using macrogenomics. To further investigate the relationship between muscone's mechanism of action and intestinal flora, the ABX hypoxia mice model was employed, alongside in vitro experiments to evaluate muscone's effect on the growth of Results: Muscone markedly alleviated hypoxia-induced inflammation improved hematological parameters, and reshaped gut microbiota composition, with a notable increase in the abundance of Conclusion: Muscone may alleviate acute high-altitude gastrointestinal stress by enhancing the abundance of
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