Evidence map›Paper›PMID 40453944›Full record

ArticleVeterinary world2025

Preliminary study of canine distemper virus transmission from small mammals to Malayan tiger at Kampung Besul Lama, Terengganu, Malaysia.

Bryan Andrew Lazarus, Muhammad Farris Mohd Sadali, Farina Mustaffa Kamal, Khor Kuan Hua, Ridhwan Abdul Wahab, Mohd Arifin Kaderi, Mohd Lutfi Abdullah, Tengku Rinalfi Putra Tengku Azizan, Hafandi Ahmad

Abstract read
In one paragraph

Article in Veterinary world, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Bryan Andrew LazarusDepartment of Veterinary Preclinical Sciences, Faculty of Veterinary Medicine, Universiti Putra Malaysia, 43400, UPM Serdang, Selangor, Malaysia.
Muhammad Farris Mohd SadaliDepartment of Veterinary Pathology and Microbiology, Faculty of Veterinary Medicine, Universiti Putra Malaysia, 43400, UPM Serdang, Selangor, Malaysia.
Farina Mustaffa KamalDepartment of Veterinary Pathology and Microbiology, Faculty of Veterinary Medicine, Universiti Putra Malaysia, 43400, UPM Serdang, Selangor, Malaysia.
Khor Kuan HuaDepartment of Clinical Studies, Faculty of Veterinary Medicine, Universiti Putra Malaysia, 43400, UPM Serdang, Selangor, Malaysia.
Ridhwan Abdul WahabFaculty of Health Sciences, University College of Malaysian Federal Territory Islamic Religious Council (MAIWP) International, Taman Batu Muda, 68100 Batu Caves, Kuala Lumpur, Malaysia.
Mohd Arifin KaderiDepartment of Biomedical Science, Kulliyyah of Allied Health Sciences, International Islamic University Malaysia, Kuantan Campus, Jalan Sultan Ahmad Shah, 25200 Kuantan, Pahang.
Mohd Lutfi AbdullahNational Wildlife Forensic Laboratory, ex situ Conservation Division, Department of Wildlife and National Parks Peninsular Malaysia, Kuala Lumpur, Malaysia.
Tengku Rinalfi Putra Tengku AzizanDepartment of Veterinary Preclinical Sciences, Faculty of Veterinary Medicine, Universiti Putra Malaysia, 43400, UPM Serdang, Selangor, Malaysia.
Hafandi AhmadDepartment of Veterinary Preclinical Sciences, Faculty of Veterinary Medicine, Universiti Putra Malaysia, 43400, UPM Serdang, Selangor, Malaysia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aim: The increasing human-wildlife interface due to urbanization and agricultural expansion has escalated the risk of zoonotic and interspecies disease transmission. Canine distemper virus (CDV), a highly contagious Materials and Methods: Wildlife sampling was conducted between July 2023 and May 2024 in Kampung Besul Lama, where CDV was previously detected in a Malayan tiger. A total of 77 small mammals from different species were captured using baited live traps. Species identification was performed based on morphological characteristics. Biological samples were collected through nasal and ocular swabs and analyzed using reverse transcription polymerase chain reaction to detect CDV RNA. Positive isolates were subjected to sequencing and Nucleotide Basic Local Alignment Search Tool analysis for molecular characterization. Results: Molecular detection confirmed CDV RNA in three common tree shrews ( Conclusion: This study provides the first molecular evidence of CDV infection in tree shrews, highlighting their potential role in sustaining CDV in an enzootic state and acting as a conduit for interspecies transmission. Given the critically endangered status of Malayan tigers, targeted CDV surveillance and One Health-based disease mitigation strategies are essential to prevent further spillover events that could accelerate species decline.

Indexed as

canine distemper virusMalayan tigermolecular detectionsmall mammalswildlife conservationzoonotic spillover

Identifiers

PMID40453944
PMCPMC12123287

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.