Evidence map›Paper›PMID 40453809›Full record

ArticleFrontiers in digital health2025

Developing a transparent reporting tool for AI-based diagnostic prediction models of disease and syndrome in Chinese medicine: a Delphi protocol.

Jieyun Li, Wei Song Seetoh, Jiekee Lim, Xin'ang Xiao, Kehu Yang, Si Yong Yeo, Boyun Sun, Jinhua Liu, Zhaoxia Xu, Linda L D Zhong

Abstract read
In one paragraph

Article in Frontiers in digital health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jieyun Li *School of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Wei Song Seetoh *School of Biological Sciences, Nanyang Technological University, Singapore, Singapore.
Jiekee LimSchool of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Xin'ang XiaoSchool of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Kehu YangEvidence Based Medicine Centre, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China.
Si Yong YeoMedVisAl Lab, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
Boyun SunDepartment of Gastroenterology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Jinhua LiuMedVisAl Lab, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
Zhaoxia XuSchool of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Linda L D ZhongSchool of Biological Sciences, Nanyang Technological University, Singapore, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The application of artificial intelligence in diagnostic prediction models for diseases and syndromes in Chinese Medicine (CM) has been rapidly expanding, accompanied by a significant increase in related research publications. However, existing reporting guidelines for diagnostic prediction models are primarily tailored to Western medicine, which differs fundamentally from CM in its theoretical framework, terminology, and classification systems. To address this gap, it is essential to establish a transparent and standardized reporting tool specifically designed for CM diagnostic and syndrome prediction models. This will enhance the transparency, reproducibility, and clinical relevance of research findings in this emerging field. Methods: This study adopts a structured, multi-phase Delphi protocol. A core working group will first conduct a comprehensive review of published studies on CM diagnostic prediction models to develop an initial item pool for the Transparent Reporting Tool for AI-based Diagnostic Prediction Models of Disease and Syndrome in Chinese Medicine (TRAPODS-CM). Delphi questionnaires will then be distributed via email to a multidisciplinary panel of experts in CM, computer science, and evidence-based methodology who meet the inclusion criteria. The number of Delphi rounds will be determined by evaluating the active coefficient, expert authority, and expert consensus. Final consensus on the TRAPODS-CM checklist will be achieved through online meetings. The study will be governed by a Steering Committee, with the core working group responsible for implementation. After publication, the finalized checklist will be disseminated via multimedia platforms, seminars, and academic conferences to maximize its academic and clinical impact. Ethics and Dissemination: This project has received ethical approval from the National Natural Science Foundation of China (Grant No. 82374336) and the Institutional Review Board of Nanyang Technological University (IRB-2024-1007). The study findings will be disseminated through peer-reviewed publications.

Indexed as

artificial intelligenceChinese medicine diagnosticsDelphi methodpredictive modelreporting guideline development

Identifiers

PMID40453809
PMCPMC12122445

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.