Evidence map›Paper›PMID 40453781›Full record

ArticleChem catalysis2024

Copper-Catalyzed 1,4-Aminohydroxylation and Aminothiolation of 1,3-Dienes by Carbonyl-Assisted Migration.

Noah H Watkins, Yungeun Kwon, Qiu Wang

Abstract read
In one paragraph

Article in Chem catalysis, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Copper-Catalyzed Three-Component Selective 1,4-Amino Oxygenation of 1,3-Dienes.Angewandte Chemie (International ed. in English) · 2026
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Noah H WatkinsDepartment of Chemistry, Duke University, NC, 27708, USA.
Yungeun KwonDepartment of Chemistry, Duke University, NC, 27708, USA.
Qiu WangDepartment of Chemistry, Duke University, NC, 27708, USA.

Funding

New Methods for the Synthesis and Study of Bioactive Nitrogen-Containing MoleculesR01GM118786 · NIGMS · DUKE UNIVERSITY · PI WANG, QIU · 2017 to 2024
$2.6M
NIGMS NIH HHS R01 GM118786
6 · The paper itself

Abstract

We report a copper-catalyzed 1,4-selective aminooxygenation of 1,3-dienes as a direct entry to 1,4-allylic amino alcohols. The reactions are effective on a diverse range of amide, urea, and ester-containing 1,3-dienes, allowing for facile installation of aliphatic alkylamines and free alcohol. The transformation was initiated by a copper-catalyzed electrophilic amination using

Identifiers

PMID40453781
PMCPMC12124767

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.