ArticleJournal of maxillofacial and oral surgery2025
Upper Airway Morphologic Changes in Rubinstein-Taybi Syndrome After Orthognathic Surgery: A Case Report.
Article in Journal of maxillofacial and oral surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Rubinstein-Taybi syndrome (RTS) is a genetic disease characterized by important developmental changes, among which craniofacial abnormalities with negative repercussions on the volume of the upper airways stand out. The treatment of dentofacial deformities associated with TRS in adulthood includes orthognathic surgery to correct the positioning of the jaws, providing functional benefits such as adequate dental occlusion, stability of mandibular movements and airways expansion. The aim of this report is to present the management of an adult individual with RTS who presented significant craniofacial deformity, severe obstructive sleep apnea and sequelae from previous surgical interventions. Methods: The recommended treatment consisted of performing bimaxillary orthognathic surgery for maxillomandibular advancement, combined with a new total reconstruction of the temporomandibular joints with customized prostheses. Results: The 3-year postoperative follow-up reveals the functional stability of the therapeutic proposal with substantial improvement in quality of life. Conclusion: The management of changes from Rubinstein-Taybi syndrome stills as a challenge. The orthognathic surgery associated with total reconstruction of the TMJs with customized prostheses provided correction of skeletal changes in the face of the individual with Rubinstein-Taybi syndrome in this case, with evident improvement in chewing and breathing, as well as aesthetic improvement reported by patient.
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