Evidence map›Paper›PMID 40453496›Full record

ArticleFrontiers in public health2025

Psychiatric drugs dispensing trends in the affected population following Brumadinho dam failure.

Marcelo Farah Dell'Aringa, Gabriel Elias Correa-Oliveira, Francesco Della Corte, Luca Ragazzoni, Ives Hubloue, Virginia Murray, Thais Piazza, Claudia Garcia Serpa Osorio-de-Castro, Elaine Miranda, Francesco Barone-Adesi

Abstract read
In one paragraph

Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Marcelo Farah Dell'AringaCRIMEDIM - Center for Research and Training in Disaster Medicine, Humanitarian Aid and Global Health, Università del Piemonte Orientale, Novara, Italy.
Gabriel Elias Correa-OliveiraNeuroscience and Behaviour Department, Universidade de Sao Paulo, Ribeirao Preto, Brazil.
Francesco Della CorteCRIMEDIM - Center for Research and Training in Disaster Medicine, Humanitarian Aid and Global Health, Università del Piemonte Orientale, Novara, Italy.
Luca RagazzoniCRIMEDIM - Center for Research and Training in Disaster Medicine, Humanitarian Aid and Global Health, Università del Piemonte Orientale, Novara, Italy.
Ives HubloueReGEDiM - Research Group on Emergency & Disaster Medicine, Vrije Universiteit Brussel, Brussels, Belgium.
Virginia MurrayUK Health Security Agency, Global Disaster Risk Reduction, London, United Kingdom.
Thais PiazzaDepartamento de Gestão e Incorporação de Tecnologias em Saúde (DGITS), Secretaria de Ciência, Tecnologia e Inovação e do Complexo Econômico-Industrial da Saúde (SECTICS), Ministério da Saúde, Brasília, Brazil.
Claudia Garcia Serpa Osorio-de-CastroEscola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz, Rio de Janeiro, Brasil.
Elaine MirandaFaculdade de Farmácia, Universidade Federal Fluminense, Niterói, Brasil.
Francesco Barone-AdesiCRIMEDIM - Center for Research and Training in Disaster Medicine, Humanitarian Aid and Global Health, Università del Piemonte Orientale, Novara, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: In January 2019 D1 tailing Dam Failed in Brumadinho, Minas Gerais, Brazil. Two hundred and seventy people were immediately killed when 11.7 million cubic meters of mining byproducts were released, promoting major destruction and environmental damage traveling through the Paraopeba river basin. This study aims to investigate the impact of this disaster in the dispensing of psychiatric drugs. Methods: We evaluated monthly aggregated data from 12 months before to 12 months after the event from two data sources, one accounting for psychiatric drugs dispensed by private pharmacies and the other by public health services. We compared the median dispensing of benzodiazepines and antidepressants from the periods before and after the event using the Mann Whitney test and performed a visual analysis of line graphs from both datasets. Results: Data shows an increase of 294% in dispensing of benzodiazepines in the month following the event with a return almost to the baseline subsequently. When comparing the periods before and after the event the increase was not statistically significant, going from 16.03 to 20.60 daily defined daily doses (DDD) per 1,000 inhabitants ( Discussion: We observed a peak in the dispensing of benzodiazepines in the month following the event drawn by the dispensing of diazepam in the public health sector. Dispensing of both benzodiazepines and antidepressants tended to be higher in the period following the event. Our findings should be taken carefully due to the nature of the data used for the study. This study can serve as a call for more evidence and local guidelines on acute psychiatric pharmacological care following disasters and for better integration of pharmaceutical assistance in disaster plans.

Indexed as

Antidepressive AgentsDisastersPsychotropic DrugsBenzodiazepinesBrazilHumansAntidepressive AgentsBenzodiazepinesPsychotropic Drugsdisaster medicinemental healthmental health policypharmaceutical assistancepublic healthpublic health datapublic mental health (PMH)

Identifiers

PMID40453496
PMCPMC12124140

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.