ArticleMacromolecules2025
MaDDFLOSY(Mass Determination via Diffusion in FLow Ordered SpectroscopY) for the Determination of Diffusion-Averaged Molecular Weight of Polymers in Continuous Motion Using Benchtop NMR.
Article in Macromolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Article
- Beyond Traditional RAFT Polymerization: Emerging Strategies and Future Perspectives; A Third Update.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- High-dimensional continuous action space control via trust region optimized deep reinforcement learning.Scientific reports · 2025Article
- Global Characterization of Commercial Generation 0-7 Poly(amidoamine) Dendrimers: Challenges and Opportunities for Analysis.ACS omega · 2025Article
- Online GPC monitoring for batch and flow polymerisation reactions.Polymer chemistry · 2025Article
Corrections and comments
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Authors and funding
9 authors.
Funding
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Abstract
Real-time determination of the molecular weight of polymers synthesized in continuous flow or indeed in any process is essential for efficient and sustainable process chemistry. Typically achieved through online chromatographic techniques, such methods are often prone to perturbations, require large volumes of solvents, have lengthy acquisition times, and can result in significant process inefficiencies. We demonstrate the use of diffusion-ordered NMR spectroscopy (DOSY NMR) calibration on a 60 MHz benchtop to measure the molecular weight of polymers while in laminar flow. We then utilized this technique to monitor batch polymerization progress in real time.
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Registered trials
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