Evidence map›Paper›PMID 40453458›Full record

ArticleTransboundary and emerging diseases2025

A Spanish Porcine Reproductive and Respiratory Syndrome Virus 1 Strain Is Highly Virulent in Pigs Under Experimental Conditions.

Paula Curto, Ariadna Pey, Alba Trabal, Elisabet Aulinas, Jordi Baliellas, Gustavo Ramírez, Jéssica Molín, Larysa Muzykina, Maria Montoya, Ramona N Pena and 2 more

Abstract read
In one paragraph

Article in Transboundary and emerging diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Paula CurtoDepartment of Animal Science (ETSEA), Universitat de Lleida-AGROTECNIO-CERCA Centre, Lleida, Spain.
Ariadna PeyA.M. Animalia Bianya, S.L., La Vall de Bianya, Spain.
Alba TrabalA.M. Animalia Bianya, S.L., La Vall de Bianya, Spain.
Elisabet AulinasA.M. Animalia Bianya, S.L., La Vall de Bianya, Spain.
Jordi BaliellasGrup de Sanejament Porcí (GSP), Lleida, Spain.
Gustavo RamírezDepartment of Animal Science (ETSEA), Universitat de Lleida-AGROTECNIO-CERCA Centre, Lleida, Spain.
Jéssica MolínDepartment of Animal Science (ETSEA), Universitat de Lleida-AGROTECNIO-CERCA Centre, Lleida, Spain.
Larysa MuzykinaMolecular Biomedicine Department, The Margarita Salas Center for Biological Research (CIB) of the Spanish National Research Council (CSIC), Madrid, Spain.
Maria MontoyaMolecular Biomedicine Department, The Margarita Salas Center for Biological Research (CIB) of the Spanish National Research Council (CSIC), Madrid, Spain.
Ramona N PenaDepartment of Animal Science (ETSEA), Universitat de Lleida-AGROTECNIO-CERCA Centre, Lleida, Spain.
Lorenzo FraileDepartment of Animal Science (ETSEA), Universitat de Lleida-AGROTECNIO-CERCA Centre, Lleida, Spain.
Ana M M StoianDepartment of Animal Science (ETSEA), Universitat de Lleida-AGROTECNIO-CERCA Centre, Lleida, Spain.ORCID https://orcid.org/0000-0002-6687-7134

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Porcine reproductive and respiratory syndrome (PRRS) remains one of the most important infectious diseases affecting the global pig industry. The emergence of highly pathogenic PRRS virus 1 (PRRSV-1) strains, first detected in northeastern Spain in 2020, poses new challenges for effective disease control. Despite their severe impact under field conditions, a comprehensive experimental characterization of these virulent strains has been lacking. In this study, we analyzed the genetic characteristics of the Lleida 029_22 strain, collected during a severe PRRSV-1 outbreak, and evaluated its pathogenicity in pigs. Phylogenetic analysis revealed that the Lleida 029_22 strain belongs to a new clade describing multiple strains isolated during a PRRSV-1 Rosalia-related outbreak, with the highly pathogenic Italian strain PR40 identified as a common ancestor.

Indexed as

Porcine Reproductive and Respiratory SyndromePorcine respiratory and reproductive syndrome virusAnimalsDisease OutbreaksPhylogenySpainSwineViremiaVirulenceVirus Sheddingexperimental infectionhigh-virulencepigporcine reproductive and respiratory syndrome virus

Identifiers

PMID40453458
PMCPMC12124928

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.