Evidence map›Paper›PMID 40453358›Full record

ArticleExperimental biology and medicine (Maywood, N.J.)2025

Tamara Timic Stamenic, Simon Feseha, Brier Fine-Raquet, Vasilije P Tadic, Slobodan M Todorovic

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental biology and medicine (Maywood, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. 2024 international conference on neuroprotective agents conference proceedings.Experimental biology and medicine (Maywood, N.J.) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tamara Timic StamenicDepartment of Anesthesiology, University of Colorado, Aurora, CO, United States.
Simon FesehaDepartment of Anesthesiology, University of Colorado, Aurora, CO, United States.
Brier Fine-RaquetDepartment of Anesthesiology, University of Colorado, Aurora, CO, United States.
Vasilije P TadicDepartment of Anesthesiology, University of Colorado, Aurora, CO, United States.
Slobodan M TodorovicDepartment of Anesthesiology, University of Colorado, Aurora, CO, United States.

Funding

The role of T-type calcium channels in the morphine effects in the nonspecific thalamusK01DA055258 · NIDA · UNIVERSITY OF COLORADO DENVER · PI Tamara Timic Stamenic · 2022 to 2026
$889k
NIDA NIH HHS K01 DA055258
6 · The paper itself

Abstract

Although substantial progress has been made in the last three decades towards our understanding of how general anesthetics (GAs) act at the molecular level, much less is known about how GAs cause loss of consciousness at the level of neuronal networks. The role of thalamus as an important brain region in anesthetic-induced hypnosis is relatively well established, but the specific roles of voltage-gated ion channels in different functional regions of the thalamus in anesthetic mechanisms are not well studied. To address this gap in knowledge, we selectively silenced the

Indexed as

Calcium Channels, T-TypeThalamusAnimalsGene SilencingIsofluraneMaleMiceMice, Inbred C57BLPatch-Clamp TechniquesRNA, Small InterferingCacna1g protein, mouseCalcium Channels, T-TypeIsofluraneRNA, Small Interferinganesthesiacalcium ion channelshypnosisisofluranethalamus

Identifiers

PMID40453358
PMCPMC12123693

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.