ArticleJournal of ginseng research2025
Anti-fatigue effects of Korean Red Ginseng extract in healthy Japanese adults: A randomized, double-blind, placebo-controlled study.
Article in Journal of ginseng research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The trial behind it
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Who cites it
8 citing papers in PubMed.
- Nrf2 as a therapeutic target of ginseng: A comprehensive review from preclinical evidence to clinical applications.Journal of ginseng research · 2026Review
- Emerging and underexplored ginsenosides in cancer therapy (2020-2025): Beyond cytotoxic mechanisms.Journal of ginseng research · 2026Review
- Phytocompounds with immunomodulatory activities: mechanisms, therapeutic potential, and clinical prospects.Inflammopharmacology · 2026Review
- Review
- A review of pharmacological properties and pharmacokinetic of 20(S)-protopanaxadiol.Journal of ginseng research · 2026Review
- Ginsenosides fromJournal of ginseng research · 2026Review
- Combined NY1301 and DDMP on Sleep and Autonomic Function in Summer: A Randomized Clinical Trial.Journal of clinical medicine · 2026Article
- Ginseng acetylcholine from various ginsengs and itsJournal of ginseng research · 2026Article
Corrections and comments
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Authors and funding
7 authors.
Funding
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Abstract
Background: Chronic fatigue deleteriously affects the quality of life, thereby impairing physical and social functions and subsequently leading to financial and social problems. This study investigated the anti-fatigue effects of Korean Red Ginseng (KRG) extract in healthy middle-aged Japanese adults. Methods: Forty-six participants were randomly divided into two groups (KRG and placebo). KRG (960 mg) or placebo capsules were administered for 3 weeks. The effect of KRG on fatigue was evaluated using visual analogue scale (VAS), plasma lactic acid, and cortisol levels. Results and conclusions: Three-week consumption of KRG extract resulted in a significant decrease in the fatigue VAS score compared to the placebo group (p = 0.035). No significant difference was found in plasma cortisol and lactic acid levels between the groups. There were no differences between groups in the incidence of adverse events and the results of urinalysis, hematology, and biochemistry. These findings suggest the potential of KRG extract in mitigating fatigue and the safety of KRG extracts in healthy adults.
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Registered trials
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