Evidence map›Paper›PMID 40453350›Full record

ArticleJournal of ginseng research2025

Compound K suppresses epidermal aging induced by IL-17A treatment and UVB irradiation.

A Young Kim, Ji-Yong Jung, Donghyun Kim, Jeong Hun Cho, Yong Deog Hong, Hyoung-June Kim, Si-Young Cho

Abstract read
In one paragraph

Article in Journal of ginseng research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Ginsenosides fromJournal of ginseng research · 2026
    Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

A Young KimResearch and Innovation Center, AMOREPACIFIC, Yongin, Republic of Korea.
Ji-Yong JungResearch and Innovation Center, AMOREPACIFIC, Yongin, Republic of Korea.
Donghyun KimResearch and Innovation Center, AMOREPACIFIC, Yongin, Republic of Korea.
Jeong Hun ChoResearch and Innovation Center, AMOREPACIFIC, Yongin, Republic of Korea.
Yong Deog HongResearch and Innovation Center, AMOREPACIFIC, Yongin, Republic of Korea.
Hyoung-June KimResearch and Innovation Center, AMOREPACIFIC, Yongin, Republic of Korea.
Si-Young ChoResearch and Innovation Center, AMOREPACIFIC, Yongin, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We evaluated the anti-accelerated epidermal skin aging effects of compound K (CK) on keratinocytes using IL-17A and ultraviolet B. CK restored epidermal functions and reduced the induction of pro-inflammatory cytokines by inhibiting NF-κB and p38 MAPK activation. CK plays a significant role in controlling accelerated epidermal skin aging.

Indexed as

Accelerated skin agingCompound KEpidermisIL-17AInflammagingUVB

Identifiers

PMID40453350
PMCPMC12125580

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.