Evidence map›Paper›PMID 40453328›Full record

ArticleBiomarker insights2025

Ishwerpreet Kaur Jawanda, Thomson Soni, Seema Kumari, Vijay Prabha

Abstract read
In one paragraph

Article in Biomarker insights, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ishwerpreet Kaur JawandaDepartment of Microbiology, Panjab University, Chandigarh, India.
Thomson SoniDepartment of Microbiology, Panjab University, Chandigarh, India.
Seema KumariDepartment of Microbiology, Panjab University, Chandigarh, India.
Vijay PrabhaDepartment of Microbiology, Panjab University, Chandigarh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Bacterial infections are often an overlooked factor in female infertility. Objective: To unveil Design: Mass spectrometry combined with experimental studies. Methods: VLf was obtained from female mice administered either with sperm immobilizing Results: Nano-LC-MS/MS yielded 5 distinct bacterial proteins in test group and no bacterial protein in control. Elution profile of test VLf revealed a single peak and indicated 1 protein band (~36 kDa) using SDS-PAGE that aligned with GMP reductase. VLf-protein showed impairment of sperm motility and viability in concentration-dependent manner and disrupted sperm morphology. Binding studies using FITC-labeled VLf-protein depicted presence of green fluorescence over entire surface of mouse spermatozoa. These results were akin to SIF, already isolated and characterized in our laboratory, from culture supernatant of Conclusion: This study provides novel evidence of sperm-impairing

Indexed as

infertilityLC-MS/MSsperm immobilizationStaphylococcus aureusvaginal lavage fluid

Identifiers

PMID40453328
PMCPMC12126649

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.