Improvement of Kidney Function Following Unilateral Nephrectomy in a Patient With Cardiovascular-Kidney-Metabolic (CKM) Syndrome.

Mrinal Asopa, Mohammad Kamgar, James Wilson, Sina Emami, Brian Shuch, Niloofar Nobakht

Abstract readCase Reports

In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it

0cells of the map it votes in

2citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

A novel continuous-progression CKM model combined with multi-omics data integration identifies lipid metabolic drivers of disease progression.Frontiers in endocrinology · 2026
Article
Machine learning-based prediction model for 30-day readmission risk in elderly patients with type 2 diabetes mellitus and heart failure: a retrospective cohort study with SHAP interpretability analysis.Frontiers in cardiovascular medicine · 2025
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mrinal AsopaMedicine, University of California Los Angeles, Los Angeles, USA.

Mohammad KamgarMedicine, University of California Los Angeles, Los Angeles, USA.

James WilsonMedicine, University of California Los Angeles, Los Angeles, USA.

Sina EmamiMedicine, University of California Los Angeles, Los Angeles, USA.

Brian ShuchMedicine, University of California Los Angeles, Los Angeles, USA.

Niloofar NobakhtMedicine, University of California Los Angeles, Los Angeles, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular-kidney-metabolic (CKM) syndrome is a significant contributor to the progressive decline in renal function, often leading to advanced chronic kidney disease. We report a 55-year-old man with a history of obesity, diabetes, and hypertension who was diagnosed with renal cell carcinoma (RCC) and underwent unilateral nephrectomy for his treatment, which led to decreased kidney function. The patient showed signs of improvement in glomerular filtration rate (GFR) and proteinuria after weight loss with combination therapy for CKM, including renin-angiotensin-aldosterone system (RAAS) inhibitors, sodium-glucose cotransporter-2 inhibitors (SGLT-2 inhibitors), and glucagon-like peptide-1 receptor agonists (GLP-1RA).

Indexed as

albuminuria reductioncardiovascular-kidney-metabolic (ckm)glucagon-like peptide-1 receptor agonist (glp-1 ra)sodium-glucose cotransporter-2 (sglt-2) inhibitorsunilateral nephrectomy

Identifiers

PMID40453308

DOI10.7759/cureus.83263

PMCPMC12124764

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.