ArticleCureus2025
Investigation of Knowledge-Based Planning Models for Intensity-Modulated Proton Therapy With Limited Data for Brain Targets.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Development and Evaluation of Knowledge-Based Treatment Plans for Chest Wall and Regional Lymph Node Irradiation.Cureus · 2026Article
- Knowledge-based planning for intensity-modulated proton therapy of the breast and chest wall with regional lymph nodes: development, validation, and comparative evaluation of two models.Frontiers in oncology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Knowledge-based planning (KBP) in radiation therapy aims to improve the plan quality and planning efficiency. Limited training data complicate the development of KBP models for intensity-modulated proton therapy (IMPT). Clinicians face questions such as whether KBP validation is feasible on the training set and if small data sets substantially impact the resulting plan quality. This work describes the development of KBP models for brain IMPT while focusing on these key questions. Materials and methods A hundred and twenty brain IMPT plans were identified and 31 were selected for validation. Three KBP models were trained (a) KBP
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.