Evidence map›Paper›PMID 40453267›Full record

ArticleCureus2025

Exploring Environmental Triggers and Viral Associations in a Case of Severe Bullous Pemphigoid.

Alexandra Lawlor, Rachel Alef, Khaled Deeb

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Alexandra LawlorRheumatology, Kansas City University College of Osteopathic Medicine, Kansas City, USA.
Rachel AlefOsteopathic Medicine, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Davie, USA.
Khaled DeebInternal Medicine, The Veteran Affairs West Palm Beach (VA WPB), West Palm Beach, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bullous pemphigoid (BP) is an autoimmune disease characterized by pruritic blisters and plaques, primarily affecting elderly individuals. The etiology of BP is multifactorial, with several documented triggers, the extent of which is currently unknown. This case reviews currently documented BP triggers and presents a case of severe and refractory BP, whose onset and progression raise suspicion for indoor pollutants and viral infection as inciting triggers. Our patient's condition worsened despite standard therapy, highlighting the complexity of BP management. This case adds to the literature, teasing out BP pathogenesis and highlighting the complicated hospital treatment course for severe autoimmune blistering diseases.

Indexed as

autoimmune diseasebullous pemphigoiddermatologyenvironmental exposuresrheumatologyviral associations

Identifiers

PMID40453267
PMCPMC12124903

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.