ArticleRSC advances2025
Multicomponent Hosomi-Sakurai reaction on chiral, bio-based, alcohols.
Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Multicomponent Hosomi-Sakurai Reaction on Isosorbide Derivatives.Molecules (Basel, Switzerland) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The multicomponent Hosomi-Sakurai reaction, which gives homoallyl ethers from aldehydes, trimethylsilyl ethers and allyltrimethylsilane, was thoroughly studied using a bio-based aldehyde (protected 5-(hydroxymethyl)tetrahydrofuran-2-carboxyaldehyde) along with trimethylsilyl ethers derived from a variety of (mainly bio-based) alcohols. For comparison, a reactive aromatic aldehyde was also employed. These studies helped to identify the optimal conditions for each aldehyde and provided insight into the scope and limitations of this relatively underexplored multicomponent reaction, one of the few that can incorporate alcohols as diversity inputs.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.