Evidence map›Paper›PMID 40452938›Full record

ArticlePeerJ2025

Longitudinal analysis of step counts in Parkinson's disease patients: insights from a web-based application and generalized additive model.

Yuan Gu, Yishu Gong

Abstract read
In one paragraph

Article in PeerJ, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yuan GuSchool of Medicine, Stanford University, Palo Alto, CA, United States of America.
Yishu GongThe Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA, United States of America.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Parkinson's disease (PD) is a chronic neurological disorder that affects millions of people worldwide. A common motor symptom associated with PD is gait impairment, leading to reduced step count and mobility. Methods: Monitoring and analyzing step count data can provide valuable insights into the progression of the disease and the effectiveness of various treatments. In our study, the generalized additive model (GAM) was used to identify statistically significant variables for step counts. Additionally, a web application was developed as an interactive visualization tool. Results: The GAM model shows that the following variables are statistically significant for daily step counts: sex ( Conclusions: Based on the PPMI data, we find that sex, handedness, PD status of father, COVID-19 status, cohort, and the smoothing functions of age are all statistically significant for step counts. Additionally, a web application tailored specifically for step count analysis in PD patients was developed. This tool provides a user-friendly interface for patients, caregivers, and healthcare professionals to track and analyze step count data, facilitating personalized treatment plans and enhancing the management of PD.

Indexed as

Parkinson DiseaseAgedCOVID-19FemaleHumansInternetLongitudinal StudiesMaleMiddle AgedLongitudinalParkinson’s diseaseShinyStep countWeb-application

Identifiers

PMID40452938
PMCPMC12126969

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.