ArticlePeerJ2025
Exploring the outcomes of non-surgical periodontal therapy in modulating periodontal parameters, renal function, and inflammatory biomarkers in chronic kidney disease patients with periodontitis.
Article in PeerJ, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Review
- The Impact of Chronic Kidney Disease on Oral Health: A Narrative Review.Journal of clinical medicine · 2026Review
- Short-term assessment of non-surgical periodontal therapy reduces oral pathogens and pro-inflammatory cytokines, enhancing clinical outcomes in patients with chronic kidney disease.BMC oral health · 2026Article
- [Effect of pioglitazone on periodontitis-related renal injury in mice and its relationship with Klotho].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2026Article
- [Mechanism of silibinin in renal injury induced by periodontitis in mice].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: This comparative prospective cohort study investigated the outcomes of non-surgical periodontal therapy (NSPT) on periodontal parameters, renal function, and serum inflammatory markers in chronic kidney disease (CKD) patients with periodontitis. Methods: Participants were categorised into three groups: CKD patients with periodontitis (CKD-P, Results: The CKD-P group exhibited the highest concentration of potassium, urea, and creatinine. There were no significant differences in the periodontal pocket depth (PPD) and clinical attachment loss (CAL) means between CKD-P and P groups ( Conclusion: NSPT is effective in enhancing periodontal health, improving renal function, and decreasing systemic inflammation in CKD patients with periodontitis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.