Evidence map›Paper›PMID 40452924›Full record

ReviewPeerJ2025

Research progress and strategies for the biosynthesis of keratinocyte growth factor-2 (KGF-2) in

Chengyang Song, Guangdong Yu, Shuang Gao, Wengang Zhao, Yunpeng Wang, Nuo Xu

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in PeerJ, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chengyang SongJilin Academy of Agricultural Sciences (Northeast Agricultural Research Center of China), Institute of Agriclutural Biotechnology, Changchun, Jilin Province, China.
Guangdong YuJilin Academy of Agricultural Sciences (Northeast Agricultural Research Center of China), Institute of Agriclutural Biotechnology, Changchun, Jilin Province, China.
Shuang GaoWenzhou Medical University, School of Pharmaceutical Sciences, Wenzhou, Zhejiang Province, China.
Wengang ZhaoWenzhou University, College of Life and Environmental Science, Wenzhou, Zhejiang Province, China.
Yunpeng WangJilin Academy of Agricultural Sciences (Northeast Agricultural Research Center of China), Institute of Agriclutural Biotechnology, Changchun, Jilin Province, China.
Nuo XuWenzhou University, College of Life and Environmental Science, Wenzhou, Zhejiang Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review examines the current research progress of molecular agriculture for cytokine expression, the research status of keratinocyte growth factor-2 (KGF-2) for skin care, hair growth, and the research status of plants for hair growth. KGF-2 application and use are inhibited by factors, such as the cost of production and efficacy due to low transdermal penetration potential. However, cell penetrating peptides (CPPs) are powerful transporter tools that assist the transmembrane delivery of attached biomacromolecules. Biomacromolecules such as KGF-2 have poor transdermal ability, which can be enhanced by combining with CPP such as TD1 to construct fusion proteins.

Indexed as

ArabidopsisFibroblast Growth Factor 10Cell-Penetrating PeptidesHumansPlants, Genetically ModifiedRecombinant Fusion ProteinsCell-Penetrating PeptidesFibroblast Growth Factor 10Recombinant Fusion ProteinsArabidopsis thalianaHair growthKGF-2Molecular farmingPlantSkin careTransdermal peptide

Identifiers

PMID40452924
PMCPMC12124295

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.