ArticleFood science & nutrition2025
Exploring Antioxidant Synergism Mechanism of 3D Printing Based Shanyao-Fuling-Yiyiren Decoction via Fuzzy Mathematical Method, Network Pharmacology, and In Vitro Experimental Validation.
Article in Food science & nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Herbal polysaccharides-a rising star in engineering multifunctional biomaterials for tissue repair and regeneration.Regenerative biomaterials · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study demonstrates the antioxidative stress potential of Shanyao-Fuling-Yiyiren (SFY) decoction-a Chinese polyherbal formulation derived from Si Fang decoction-by establishing a systematic framework that integrates network pharmacology, molecular docking, in vitro synergy assays, cellular experiments, and 3D printing. Despite its long traditional use, the molecular and cellular mechanisms underlying its antioxidative effects remain unclear, and its formulations are based more on empirical methods than on systematic design. To fill this gap, a fuzzy mathematical model was used to select the optimal polyherbal combination. A central composite circumscribed design determined that a Shanyao:Fuling:Yiyiren ratio of 2:2:1 maximized radical scavenging, with a strong correlation (
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.