Evidence map›Paper›PMID 40452749›Full record

ArticlePaediatrics & child health2025

Lauren Dagyung Lee, Nirma Khatri Vadlamudi, Katherine Yu, Manish Sadarangani, Nicole Le Saux, Joanne Embree, James D Kellner, Shaun K Morris, Scott A Halperin, Julie A Bettinger and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Paediatrics & child health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lauren Dagyung LeeCumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.ORCID https://orcid.org/0009-0000-3242-3436
Nirma Khatri VadlamudiVaccine Evaluation Center, BC Children's Hospital Research Institute, Vancouver, British Columbia, Canada.ORCID https://orcid.org/0000-0001-5513-7926
Katherine YuCumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Manish SadaranganiVaccine Evaluation Center, BC Children's Hospital Research Institute, Vancouver, British Columbia, Canada.
Nicole Le SauxDivision of Infectious Diseases, Department of Pediatrics, Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ontario, Canada.ORCID https://orcid.org/0000-0002-0817-3526
Joanne EmbreeDepartment of Pediatrics and Child Health, University of Winnipeg, Winnipeg, Manitoba, Canada.
James D KellnerDepartment of Pediatrics, University of Calgary, Calgary, Alberta, Canada.
Shaun K MorrisDivision of Infectious Diseases, Department of Paediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
Scott A HalperinCanadian Center for Vaccinology, Halifax, Nova Scotia, Canada.
Julie A BettingerVaccine Evaluation Center, BC Children's Hospital Research Institute, Vancouver, British Columbia, Canada.ORCID https://orcid.org/0000-0002-2118-4174
for Members of the Canadian Immunization Monitoring Program, Active (IMPACT)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Methods: The Canadian Immunization Monitoring Program, ACTive (IMPACT) is a national surveillance network for vaccine-preventable diseases. All confirmed IPD cases from 1991 through 2019 were included in the analysis. IPD cases with new HUS diagnoses were identified as SPHUS cases, and the rest as non-HUS IPD. Results: There were 30 (0.4%) cases of SP-HUS amongst 6757 IPD cases. The median age of SP-HUS cases was 27.5 months, with no significant differences between SP-HUS and non-HUS cases in age or sex. Conclusions: SP-HUS was usually seen in IPD cases with pneumonia and was most commonly caused by serotypes 3 and 19A. ICU care was lengthy, hospital stay was longer. No deaths occurred among SP-HUS cases.

Indexed as

Atypical hemolytic uremic syndromeCanadaIMPACTInvasive pneumococcal diseaseNon-STEC hemolytic uremic syndrome

Identifiers

PMID40452749
PMCPMC12122207

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.