ArticleCureus2025
A Case of Fatal Herpes Simplex Virus 1 Encephalitis Complicated by Status Epilepticus: From Elective Phlebectomy to Intensive Care.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Herpes simplex encephalitis is most commonly caused by herpes simplex virus type 1 (HSV-1) and is believed to result from retrograde transport along the trigeminal and olfactory nerves into the central nervous system. This case report presents a 73-year-old female who arrived at the emergency department following the acute onset of confusion before an elective outpatient procedure. Her initial physical examination and diagnostic workup were unremarkable. By day six of hospitalization, the patient became progressively obtunded, with significant clinical deterioration marked by a Glasgow Coma Scale score of 5 and recurrent episodes of high-grade fever. Magnetic resonance imaging revealed inflammation and hyperintensities in the right frontotemporal lobes, highly suggestive of HSV encephalitis, and cerebrospinal fluid analysis confirmed HSV-1 infection. This case report discusses the rapid clinical progression of HSV-1 encephalitis, highlights potential complications, and reviews the acute management of a patient with a poor prognosis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.