Evidence map›Paper›PMID 40452476›Full record

ArticleInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2025

Initial experience of utilizing a lower-profile transradial approach for mechanical thrombectomy: Comparable efficacy to larger-bore transfemoral approaches.

Mohammad-Mahdi Sowlat, Zachary S Hubbard, Ariana Chacon, Conor M Cunningham, Rahim Abo Kasem, Julio Isidor, Jonathan R Lena, Alejandro M Spiotta

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Article in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Mohammad-Mahdi SowlatDepartment of Neurosurgery, Medical University of South Carolina, Charleston, SC, USA.
Zachary S HubbardDepartment of Neurosurgery, Medical University of South Carolina, Charleston, SC, USA.ORCID 0000-0002-5643-9480
Ariana ChaconDepartment of Neurosurgery, Medical University of South Carolina, Charleston, SC, USA.ORCID 0000-0003-2005-5781
Conor M CunninghamDepartment of Neurosurgery, Medical University of South Carolina, Charleston, SC, USA.
Rahim Abo KasemDepartment of Neurosurgery, Medical University of South Carolina, Charleston, SC, USA.ORCID 0000-0002-9635-7471
Julio IsidorDepartment of Neurosurgery, Medical University of South Carolina, Charleston, SC, USA.ORCID 0000-0002-3138-3484
Jonathan R LenaDepartment of Neurosurgery, Medical University of South Carolina, Charleston, SC, USA.
Alejandro M SpiottaDepartment of Neurosurgery, Medical University of South Carolina, Charleston, SC, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundWhile transfemoral access is commonly used for mechanical thrombectomy (MT) due to large-bore catheters providing greater aspiration forces, some centers employ transradial access (TRA) in select cases with favorable anatomy. We report our institutional experience to evaluate the efficacy of using TRA as the default approach for large-vessel occlusion (LVO) with a streamlined, lower-profile system.MethodsA retrospective review was conducted on 23 consecutive thrombectomies performed via TRA, regardless of patient anatomy or LVO location. Demographic and procedural variables were collected.ResultsAmong the 23 patients (median age 72 years; 52% female; 57% white), occlusions were primarily in the M1 territory (44%) and carotid terminus artery (13%). The average time to first pass was 10 ± 7.7 min, and time to recanalization (thrombolysis in cerebral infarction [TICI] ≥2b) was 16 ± 12.5 min. Intracranial atherosclerosis requiring stenting or balloon angioplasty occurred in 20% of cases. For these patients, mean recanalization time was 17 ± 13.6 min; for those requiring thrombectomy alone, it was 8.8 ± 5.1 min, all achieving TICI ≥2b in a single pass. Final TICI scores were 3 in 73% of cases, 2c in 23%, and 2b in 4%.ConclusionA streamlined, lower-profile TRA system can effectively serve as an upfront modality for MT and appears to perform comparably to larger-bore, transfemoral alternatives. This technique offers the benefits of TRA without compromising efficacy.

Indexed as

acute ischemic strokelarge-vessel occlusionmechanical thrombectomyTransradial approach

Identifiers

PMID40452476
PMCPMC12129943

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.