Evidence map›Paper›PMID 40452472›Full record

SynthesisInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2026

Diagnostic value of non-invasive large vessel occlusion detection methods: A systematic review and meta-analysis.

Seyed Behnam Jazayeri, Mohammad Mehdi Mehrabi Nejad, Sherief Ghozy, Noha Hamouda, Baria Ahmad, Ramanathan Kadirvel, David F Kallmes

Expression of concernAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It carries an expression of concern. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Seyed Behnam JazayeriTehran University of Medical Sciences, Tehran, Iran.ORCID 0000-0003-2860-6496
Mohammad Mehdi Mehrabi NejadDepartment of Radiology, Advanced Diagnostic and Interventional Radiology Research Center (ADIR), Tehran University of Medical Sciences, Tehran, Iran.ORCID 0000-0002-2452-0495
Sherief GhozyDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0001-5629-3023
Noha HamoudaDepartment of Radiology, Alexandria University, Alexandria, Egypt.ORCID 0000-0001-7835-0594
Baria AhmadFaculty of Medicine in Hradec Králové, Charles University, Prague, Czech Republic.ORCID 0009-0007-1014-9772
Ramanathan KadirvelDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0002-6786-9953
David F KallmesDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0002-8495-0040

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundAccurate and timely prehospital detection of large vessel occlusion (LVO) is critical for optimizing patient triage and initiating appropriate reperfusion therapies. Recent advances in portable stroke detection technologies, such as electroencephalography (EEG) and transcranial Doppler (TCD) ultrasound, offer potential solutions but their diagnostic performance remains unclear.MethodsWe searched PubMed, Scopus, Embase, and Web of Science, following the PRISMA guidelines. Studies were included if they assessed the diagnostic performance of non-invasive prehospital LVO detection tools compared to CT or MR angiography. Risk of bias was assessed using the QUADAS-2 tool.ResultsA total of 13 studies were included, examining various portable detection tools including EEG or neurophysiological monitoring, ultrasound-based techniques including TCD or TCCD, portable Openwater optical blood flow monitor and cranial accelerometry. The pooled diagnostic odds ratio (DOR) was 52.7 (95% CI: 28.3-97.8), indicating strong diagnostic performance, with significant heterogeneity among studies (I

Indexed as

StrokeElectroencephalographyHumansSensitivity and SpecificityUltrasonography, Doppler, TranscranialDopplerelectroencephalographyemergency medical servicesStroketranscranialtriageultrasonography

Identifiers

PMID40452472
PMCPMC12129949

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.