Evidence map›Paper›PMID 40452419›Full record

ArticleInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2025

Adjunctive intra-arterial thrombolysis after thrombectomy: Findings from the RITE registry.

Samar Eshetawe, Alaa Hijji, Sarah Almejaiwl, Mohammad Alqahtani, Fawaz F Alotaibi, Saida Mohammad, Hani Alabdely, Abdelmajeed Alanazi, Nouf Almansour, Abdullah Alrashed and 8 more

Abstract read
In one paragraph

Article in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Intra-arterial tenecteplase in acute ischemic stroke after successful endovascular thrombectomy: a meta-analysis of randomized controlled trials.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Samar EshetaweNeuroscience Center, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.ORCID 0009-0002-5408-4708
Alaa HijjiNeuroscience Center, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
Sarah AlmejaiwlDepartment of Biostatistics, Epidemiology and Scientific Computing, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.ORCID 0009-0006-7396-9631
Mohammad AlqahtaniNeuroscience Center, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.ORCID 0000-0003-4521-2501
Fawaz F AlotaibiNeuroscience Center, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
Saida MohammadDepartment of Neurology, King Saud Medical City, Riyadh, Saudi Arabia.
Hani AlabdelyDepartment of Neurology, King Saud Medical City, Riyadh, Saudi Arabia.
Abdelmajeed AlanaziDepartment of Neurology, King Saud Medical City, Riyadh, Saudi Arabia.
Nouf AlmansourDepartment of Neurology, King Saud Medical City, Riyadh, Saudi Arabia.
Abdullah AlrashedDepartment of Radiology, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
Riyadh AlakiliDepartment of Radiology, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
Ammar AlKawiNeuroscience Center, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.ORCID 0000-0002-3606-2962
Abdulrahman A AlreshaidNeuroscience Center, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
Mohamed AlZawahmahNeuroscience Center, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
Adel AlHazzaniNeuroscience Center, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
Ashfaq ShuaibDepartment of Medicine, Division of Neurology, University of Alberta, Edmonton, Canada.
Anas AlrohimiNeuroscience Center, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.ORCID 0000-0001-7601-6920
Fahad S Al-AjlanNeuroscience Center, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundDespite the excellent recanalization rates following thrombectomy, significantly fewer patients have favorable outcomes. Impaired reperfusion of the microcirculation caused by distal thrombi could contribute to that, and adjunctive intraarterial thrombolysis such as alteplase (IA-tPA) might improve outcomes. We assessed the impact of adjunctive IA-tPA following thrombectomy with TICI score

Indexed as

endovascular thrombectomyintraarterial thrombolysisIschemic strokelarge vessel occlusionTICI

Identifiers

PMID40452419
PMCPMC12129940

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.