Evidence map›Paper›PMID 40452385›Full record

ArticleHead & neck2025

Examining the Relationship Between Dysphagia, Eating-Related Symptoms, and Diet Quality Among Oropharyngeal Cancer Patients During Critical Stages of Cancer Survivorship: The U-DINE Study.

Beatrice Manduchi, Vlad C Sandulache, Ji Yun Tark, Shreela Sharma, Ruosha Li, Emily Roller, Andrew Bevelhimer, Katherine A Hutcheson, Marcia C de Oliveira Otto

Abstract read
In one paragraph

Article in Head & neck, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. A cross-sectional retrospective and prospective service evaluation of head and neck cancer patients' swallowing and quality of life concerns: are we doing enough?Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Beatrice ManduchiDepartment of Epidemiology, The University of Texas Health Science Center at Houston School of Public Health, Houston, Texas, USA.ORCID 0000-0001-8953-8373
Vlad C SandulacheBobby R. Alford Department of Otolaryngology Head and Neck Surgery, Baylor College of Medicine, Houston, Texas, USA.ORCID 0000-0002-9205-385X
Ji Yun TarkDepartment of Epidemiology, The University of Texas Health Science Center at Houston School of Public Health, Houston, Texas, USA.
Shreela SharmaCenter for Health Equity, Department of Epidemiology, The University of Texas Health Science Center at Houston School of Public Health, Houston, Texas, USA.
Ruosha LiDepartment of Epidemiology, The University of Texas Health Science Center at Houston School of Public Health, Houston, Texas, USA.
Emily RollerSpeech Pathology Section, Rehabilitation and Extended Care Line, Michael E. DeBakey Veterans Affairs Medical Center, Houston, Texas, USA.
Andrew BevelhimerSpeech Pathology Section, Rehabilitation and Extended Care Line, Michael E. DeBakey Veterans Affairs Medical Center, Houston, Texas, USA.
Katherine A HutchesonDepartment of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.ORCID 0000-0003-3710-5706
Marcia C de Oliveira OttoDepartment of Epidemiology, The University of Texas Health Science Center at Houston School of Public Health, Houston, Texas, USA.ORCID 0000-0002-4585-0688

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Fabien Delerue · 1985 to 2026
$290.8M
Project 3: OPC-RADP01CA285249 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Clifton David Fuller, Katherine Arnold Hutcheson · 2024 to 2026
$9.4M
Charles and Daneen Stiefel Oropharynx Cancer FundDepartment of Defense W81XWH-21-1-0243National Institute of Health, National Cancer Institute 1P01CA285249NCI NIH HHS P01 CA285249NCI NIH HHS P30 CA016672The MD Anderson Cancer Center Support Grant Biostatistics Resource Group P30CA016672UTHealth Houston Innovation for Cancer Prevention Research Training Program Postdoctoral Fellowship (Cancer Prevention and Research Institute of Texas) RP210042
6 · The paper itself

Abstract

backgroundDiet quality is a modifiable factor impacting treatment outcomes in oropharyngeal cancer (OPC), yet the effect of dysphagia and self-reported eating-related symptoms remains unclear. This study examined their associations with diet quality in OPC patients.

methodsA cross-sectional analysis was conducted with two parallel cohorts from MD Anderson Cancer Center and Michael E. DeBakey Veterans Affairs Medical Center as part of the Uncovering the Long-Term Impact of OPC and Dysphagia on Dietary Quality and Nutrition Among Cancer Survivors (U-DINE) Study. Participants at varying survivorship stages (prediagnosis, 3-6 and 18+ months posttreatment) were assessed for dysphagia (DIGEST scale) and six individual eating-related symptoms (MDASI-HN). Diet quality was measured using HEI-2020 scores from two 24-h dietary recalls.

resultsAmong 178 survivors, mean HEI-2020 was 49.5 ± 11.3. In multivariable models, moderate-severe dysphagia (18.5% of the sample) was associated with higher diet quality (β = 7.11, p = 0.004), while eating-related symptoms showed no significant association.

conclusionsUnexpectedly, poor swallowing function correlated with better diet quality. However, overall diet quality was suboptimal, highlighting the need for interventions for all OPC survivors, regardless of swallowing function, to address diet quality as an independent risk factor throughout survivorship.

Indexed as

Cancer SurvivorsDeglutition DisordersDietOropharyngeal NeoplasmsAgedCross-Sectional StudiesFemaleHumansMaleMiddle Ageddiet qualitydysphagiahead and neckoropharyngeal cancerswallowingsymptom burden

Identifiers

PMID40452385
PMCPMC12354315

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.