Evidence map›Paper›PMID 40452336›Full record

Trial reportJournal of global health2025

A cross-sectional analysis of the impact of lady health worker visits in the prenatal and postnatal period on the uptake of continuum of care interventions and childhood mortality in Pakistan.

Shah Muhammad, Zahid A Memon, Abeer Mian, Yaqub Wasan, Arjumand Rizvi, Imran Ahmed, Sajid Soofi, Simon Cousens, Zulfiqar A Bhutta

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in Journal of global health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04184544 (Supporting Women and Girls in Pakistan), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04184544 naunknown statusnot on this map

Supporting Women and Girls in Pakistan: Scaling up Empowerment and Care Strategies to Address Health and Survival

TypeinterventionalSponsorAga Khan UniversityRan2017 to 2023Enrolled5,000,000ConditionsMaternal Complication of Pregnancy, Newborn Morbidity, Perinatal ProblemsArmsImproving of quality of care at health facility and outreach level
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shah MuhammadCentre of Excellence in Women and Child Health, The Aga Khan University, Karachi, Pakistan.
Zahid A MemonCentre of Excellence in Women and Child Health, The Aga Khan University, Karachi, Pakistan.
Abeer MianCentre of Excellence in Women and Child Health, The Aga Khan University, Karachi, Pakistan.
Yaqub WasanCentre of Excellence in Women and Child Health, The Aga Khan University, Karachi, Pakistan.
Arjumand RizviCentre of Excellence in Women and Child Health, The Aga Khan University, Karachi, Pakistan.
Imran AhmedCentre of Excellence in Women and Child Health, The Aga Khan University, Karachi, Pakistan.
Sajid SoofiCentre of Excellence in Women and Child Health, The Aga Khan University, Karachi, Pakistan.
Simon CousensLondon School of Hygiene and Tropical Medicine London, UK.
Zulfiqar A BhuttaCentre of Excellence in Women and Child Health, The Aga Khan University, Karachi, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Community health workers are crucial in bridging the gap between health care facilities and the general population. In Pakistan, the lady health worker (LHW) program was launched in 1994 to enhance access to essential health care services. However, the overall quality of care provided by LHWs and its impact on population-level coverage of key maternal, newborn, and child health (MNCH) interventions and mortality remain insufficiently understood. Methods: We conducted a cross-sectional analysis using data from 32 106 households with at least one woman of reproductive age across eight districts in Pakistan. Of these households, 63% were located within LHW catchment areas. We categorised households into three groups: 1) no contact with LHWs, 2) at least one contact during either pregnancy or post-delivery, and 3) at least one contact each during both pregnancy and post-delivery. Results: We observed a clear gradient in the uptake of pregnancy-related and MNCH interventions across the three groups. For instance, four antenatal care visits were reported as 25.3% in group A, 29.4% in group B, and 36.2% in group C (P < 0.001). Similar trend followed for skilled birth attendance; 54.4% group A, 58.7% group B, and 64.4% group C (P < 0.001). Measles vaccination coverage was 32.3% in group A, 35.2% in group B, and 49.7% in group C (P < 0.001). However, there was no evidence of significant differences in neonatal (P = 0.862), postnatal (P = 0.121), or child mortality (P = 0.319) across the three groups. Conclusions: Increased LHW contact enhances MNCH intervention uptake, though other mechanisms may contribute. Effectiveness depends on service quality, referral systems, and systemic barriers. Strengthening training, optimising referrals, and integrating community health initiatives are vital for sustainability. Addressing workforce shortages, gender challenges, and financial constraints is crucial. Future research should examine sociocultural and programmatic factors influencing health care access and outcomes. Registration: Clinicaltrials.gov NCT04184544.

Indexed as

Child MortalityCommunity Health WorkersContinuity of Patient CarePostnatal CarePrenatal CareAdolescentAdultChildChild, PreschoolCross-Sectional StudiesFemaleHumansInfantInfant, NewbornMalePakistan

Identifiers

PMID40452336
PMCPMC12127780

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.