Evidence map›Paper›PMID 40452192›Full record

ArticleJournal of musculoskeletal & neuronal interactions2025

Gross Motor Function and Musculoskeletal Deformities in Children With Congenital Zika Virus Syndrome.

Alessandro Uono Sanchez, Altair Gustavo Saura Martins, Ana Patricia Montebello Medeiros Bahé, Francisco Oliveira Zucchi, Moacir Miguel Borges de Almeida, Múcio Brandão Vaz de Almeida, Rodrigo Mendes Heilmann, Sabrina Giovana Cavalcanti Lucas, Vanessa Van der Linden, Epitácio Leite Rolim Filho

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Article in Journal of musculoskeletal & neuronal interactions, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Alessandro Uono SanchezMedical Science Center, Federal University of Pernambuco, Recife, Pernambuco, Brazil.
Altair Gustavo Saura MartinsMedical Science Center, Federal University of Pernambuco, Recife, Pernambuco, Brazil.
Ana Patricia Montebello Medeiros BahéAssociation for Assistance of Disabled Children, Recife, Pernambuco, Brazil.
Francisco Oliveira ZucchiMedical Science Center, Federal University of Pernambuco, Recife, Pernambuco, Brazil.
Moacir Miguel Borges de AlmeidaMedical Science Center, Federal University of Pernambuco, Recife, Pernambuco, Brazil.
Múcio Brandão Vaz de AlmeidaMedical Science Center, Federal University of Pernambuco, Recife, Pernambuco, Brazil.
Rodrigo Mendes HeilmannMedical Science Center, Federal University of Pernambuco, Recife, Pernambuco, Brazil.
Sabrina Giovana Cavalcanti LucasPernambuco Health College, Recife, Pernambuco, Brazil.
Vanessa Van der LindenAssociation for Assistance of Disabled Children, Recife, Pernambuco, Brazil.
Epitácio Leite Rolim FilhoMedical Science Center, Federal University of Pernambuco, Recife, Pernambuco, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe objective of the present study was to assess gross motor function and describe musculoskeletal deformities in patients diagnosed with Congenital zika syndrome (CZS).

methodsThis is a cross-sectional study, carried out at the Association for Assistance of Disabled Children (AACD) in Pernambuco, Brazil, between June 2017 and April 2023. Medical records and assessments were carried out to describe musculoskeletal deformities and measure gross motor function, using the GMFM-88.

resultsThe study included 37 patients between 1 and 2 years old, 56.8% infected during the first trimester of pregnancy. The patients' mean GMFM value was 5.63 and standard deviation was 6.37. A moderate correlation was observed between head circumference at birth and the patients' current gross motor function (Pearson coeficient = 0.594) (p<0.001). We also observed 19 types of deformities, which were more prevalent in the lower limbs.

conclusionCZS brings significant impairments to motor function and the musculoskeletal system. In this context, measuring head circumference at birth can serve as a predictor of impaired gross motor function in these children.

Indexed as

Motor SkillsMusculoskeletal AbnormalitiesZika Virus InfectionBrazilChild, PreschoolCross-Sectional StudiesFemaleHumansInfantMalePregnancyPregnancy Complications, InfectiousCongenital AbnormalitiesCongenital Zika SyndromeMotor Skills DisordersNeuromuscular ManifestationsZika Virus Infection

Identifiers

PMID40452192
PMCPMC12131074

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.