Evidence map›Paper›PMID 40451982›Full record

ArticleInternational ophthalmology2025

Evaluation of corneal asymmetry and higher-order aberrations after small incision lenticule extraction for moderate and high myopia.

Manli Deng, Dan Zhou, Min Li, Yuehui Shi, Lina Sun, Jun Zou, Xiaoyun Ma

2 registry-linked trialsAbstract read
PubMed Publisher
In one paragraph

Article in International ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07512102 narecruitingnot on this mapstarted 2026, after this paper: background citation

Comparison of Low- Versus High-Level Angle Kappa Compensation Strategies in SMILE Using the VisuMax 800: A Randomized Clinical Trial

TypeinterventionalSponsorZhongshan Ophthalmic Center, Sun Yat-sen UniversityRan2026 to 2027Enrolled100ConditionsMyopia, Refractive AmetropiaArmsApply high compensation to the Kappa angle., Apply low compensation to the Kappa angle.
NCT07512115 narecruitingnot on this mapstarted 2026, after this paper: background citation

Effect of Centration Compensation on Visual Quality in VisuMax 800 SMILE for Small Kappa Angles: A Randomized Trial

TypeinterventionalSponsorZhongshan Ophthalmic Center, Sun Yat-sen UniversityRan2026 to 2027Enrolled224ConditionsMyopia, Refractive AmetropiaArmsApply compensation to the Kappa angle., Apply no compensation to the Kappa angle
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Manli Deng *Department of Ophthalmology, Shanghai University of Medicine & Health Science Affiliated Zhou Pu Hospital, 1500 Zhouyuan Road, Shanghai, 201318, China.
Dan Zhou *Department of Ophthalmology, Shanghai University of Medicine & Health Science Affiliated Zhou Pu Hospital, 1500 Zhouyuan Road, Shanghai, 201318, China.
Min LiDepartment of Ophthalmology, Shanghai Tenth People's Hospital, Tongji University, 301 Yan Chang Middle Road, Shanghai, 200072, China.
Yuehui ShiDepartment of Ophthalmology, Shanghai Tenth People's Hospital, Tongji University, 301 Yan Chang Middle Road, Shanghai, 200072, China.
Lina SunDepartment of Ophthalmology, Shanghai Tenth People's Hospital, Tongji University, 301 Yan Chang Middle Road, Shanghai, 200072, China.
Jun ZouDepartment of Ophthalmology, Shanghai Tenth People's Hospital, Tongji University, 301 Yan Chang Middle Road, Shanghai, 200072, China. zoujun70@126.com.
Xiaoyun MaDepartment of Ophthalmology, Shanghai University of Medicine & Health Science Affiliated Zhou Pu Hospital, 1500 Zhouyuan Road, Shanghai, 201318, China. maxiaoy1820@126.com.

Funding

Key Specialty Construction Project of Pudong New Area Health Commission PWZzk2022-10Multi-Center Clinical Research Project of Shanghai Shenkang Hospital Development Center SHDC2020CR1043B-009
6 · The paper itself

Abstract

purposeTo evaluate the relationships between the magnitudes of corneal asymmetry and induced ocular higher-order aberrations (HOAs) after small-incision lenticule extraction (SMILE) for moderate-to-high myopia.

methodsSixty-six eyes of 66 patients who underwent SMILE were divided into two groups: the high (SE ≥ -6.0 D, n = 27, Group H) and moderate (- 3.0 D ≤ SE < - 6.0 D, n = 39, Group M) myopia groups. Using Fourier harmonic analysis, the spherical component (SC), regular astigmatism (RA), asymmetry, and higher-order irregularity (HOI) were obtained from videokeratography data. Visual acuity, manifest refraction, and ocular HOAs were assessed at baseline and 3, 6, and 12 months postoperatively. The relationships between Fourier components and ocular HOAs were assessed.

resultsIn both groups, vertical coma, horizontal coma, spherical aberration, total higher-order aberrations (tHOAs), and asymmetry of the anterior corneal surface increased postoperatively (from 3 to 12 months), while SC and RA of the anterior corneal surface decreased (all P < 0.05). More vertical coma and asymmetry of the anterior corneal surface were induced in Group H than in Group M at 3 and 6 months postoperatively (all P < 0.05). The association between preoperative asymmetry of the anterior corneal surface and preoperative spherical aberration was significant in both groups (R

conclusionsThe visual quality after SMILE was associated with the asymmetry of the anterior corneal surface for moderate and high myopia.

Indexed as

CorneaCorneal StromaCorneal Surgery, LaserCorneal Wavefront AberrationLasers, ExcimerMyopiaRefraction, OcularVisual AcuityAdultCorneal TopographyFemaleFollow-Up StudiesHumansMaleRetrospective StudiesYoung AdultCorneal asymmetryFourier harmonic analysisHigher-order aberrationsMyopiaSmall incision lenticule extraction

Identifiers

PMID40451982

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.