Evidence map›Paper›PMID 40451689›Full record

ArticleContact lens & anterior eye : the journal of the British Contact Lens Association2025

In vivo assessment of multifocal contact lens fitting using anterior segment optical coherence tomography.

Victor Rodriguez-Lopez, Eduardo Esteban-Ibañez, Ana Gonzalez-Ramos, Susana Marcos, Eduardo Martinez-Enriquez

Abstract read
In one paragraph

Article in Contact lens & anterior eye : the journal of the British Contact Lens Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Victor Rodriguez-LopezInstitute of Optics, Spanish National Research Council (IO-CSIC), Madrid, Spain. Electronic address: victor.rl@io.cfmac.csic.es.
Eduardo Esteban-IbañezInstitute of Optics, Spanish National Research Council (IO-CSIC), Madrid, Spain; 2EyesVision S.L., Madrid, Spain.
Ana Gonzalez-RamosInstitute of Optics, Spanish National Research Council (IO-CSIC), Madrid, Spain.
Susana MarcosInstitute of Optics, Spanish National Research Council (IO-CSIC), Madrid, Spain; Center for Visual Science, The Institute of Optics, Flaum Eye Institute, University of Rochester, NY, USA.
Eduardo Martinez-EnriquezInstitute of Optics, Spanish National Research Council (IO-CSIC), Madrid, Spain.

Funding

VISUAL SCIENCE RESEARCH CTR SUPPORTP30EY001319 · NEI · UNIVERSITY OF ROCHESTER · PI Susana Marcos · 1985 to 2026
$17.5M
Interplay between multifocal optics and accommodation: implications for myopia progressionR01EY035009 · NEI · UNIVERSITY OF ROCHESTER · PI Susana Marcos · 2023 to 2026
$2.0M
NEI NIH HHS P30 EY001319NEI NIH HHS R01 EY035009
6 · The paper itself

Abstract

Multifocal contact lenses (MCLs) are designed to provide near vision functionality in presbyopia. They rely on the correct deployment of the multifocal power profile on the cornea and on the optical interactions between the MCL and the eye. The contact lens profile on the eye and the potential conformity to the cornea was evaluated using custom-developed spectral anterior segment Optical Coherence Tomography (OCT). OCT images were obtained from one eye of 13 subjects (age: 35.7 ± 13.8 years) with naked eyes and with MCLs on the eye. All eyes were measured with the same MCLs: 1-Day Acuvue® Moist Multifocal with low, medium, and high additions. Images were processed using custom routines for segmentation, fan distortion correction, 3D model construction and quantification. The radius of curvature of the anterior and posterior surfaces of the MCLs (RAL and RPL, respectively) and the anterior surface of the naked cornea (RAC) were obtained within a 3-mm diameter central area (addition area) and within a 3-6 mm peripheral ring. The power profile was also obtained by a ray-tracing analysis. RAC ranged from 7.5 to 8.2 mm across subjects (mean 8.02 ± 0.22 mm). RAC was correlated with RPL and RAL in the periphery (r > 0.80, p < 0.05) and in the addition (r > 0.79, p < 0.05) areas for the three MCL additions. The average power profile exhibited a slightly lower addition than that reported by the manufacturer (1.32, 1.36, and 1.83 D for low, medium, and high additions), but similar to other off-eye reports in the literature. OCT equipped with quantification tools allows to study the fitting of MCLs to the eye in vivo. It was found that, overall, soft MCLs conform to the underlying cornea, in both the central and the peripheral areas, and the central near add is provided as expected.

Indexed as

Anterior Eye SegmentContact Lenses, HydrophilicCorneaPresbyopiaProsthesis FittingTomography, Optical CoherenceAdultFemaleHumansMaleMiddle AgedYoung AdultContact lens fittingMultifocal contact lensesOCTPower profilePresbyopia

Identifiers

PMID40451689
PMCPMC13315645

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.