Evidence map›Paper›PMID 40451241›Full record

Trial reportPediatrics2025

Feasibility and Acceptability of Recommending HPV Vaccine at Ages 9-10 Years.

Caroline K Tietbohl, Dennis Gurfinkel, Danielle Duran, Alison Saville, Emma Clark, Sean O'Leary, Christina Albertin, Brenda Beaty, Sitaram Vangala, Peter G Szilagyi and 1 more

Abstract readRandomized Controlled TrialMulticenter Study
In one paragraph

Trial report in Pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Caroline K TietbohlAdult and Child Center for Outcomes Research and Delivery Science, University of Colorado and Children's Hospital Colorado, Aurora, Colorado.
Dennis GurfinkelAdult and Child Center for Outcomes Research and Delivery Science, University of Colorado and Children's Hospital Colorado, Aurora, Colorado.
Danielle DuranAdult and Child Center for Outcomes Research and Delivery Science, University of Colorado and Children's Hospital Colorado, Aurora, Colorado.
Alison SavilleAdult and Child Center for Outcomes Research and Delivery Science, University of Colorado and Children's Hospital Colorado, Aurora, Colorado.
Emma ClarkDavid Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California.
Sean O'LearyAdult and Child Center for Outcomes Research and Delivery Science, University of Colorado and Children's Hospital Colorado, Aurora, Colorado.
Christina AlbertinDavid Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California.
Brenda BeatyAdult and Child Center for Outcomes Research and Delivery Science, University of Colorado and Children's Hospital Colorado, Aurora, Colorado.
Sitaram VangalaDavid Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California.
Peter G SzilagyiDavid Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California.
Allison KempeAdult and Child Center for Outcomes Research and Delivery Science, University of Colorado and Children's Hospital Colorado, Aurora, Colorado.

Funding

The HPV9-10 Trial: Early Initiation of HPV VaccinationR01CA240649 · NCI · UNIVERSITY OF COLORADO DENVER · PI KEMPE, ALLISON, SZILAGYI, PETER G · 2020 to 2024
$3.2M
NCI NIH HHS R01 CA240649
6 · The paper itself

Abstract

introductionThe human papillomavirus (HPV) vaccine is routinely recommended at ages 11-12 and may be given as early as ages 9-10 years. We assessed primary care clinician and staff experiences with feasibility and acceptability of initiating at ages 9-10 years.

methodsThis explanatory sequential mixed-methods study was part of an ongoing randomized trial comparing initiation at ages 9-10 years (intervention) vs 11-12 years (control) across 17 practices in Colorado (CO; 9 intervention) and 16 practices in California (CA; 8 intervention). We surveyed intervention practice clinicians at 1 month after study initiation and conducted semi-structured interviews at 3 months after study initiation. We used descriptive statistics to analyze surveys and content analysis for interviews.

results66 (92%) CO and 39 (87%) CA clinicians completed 1-month surveys; 59 (90%) in CO and 30 (77%) in CA were routinely initiating vaccines at age 9 or 10 years. Most reported that vaccination at ages 9-10 years was not burdensome, and issues were largely unchanged, including parental concerns and discussion times. Interviewees (18 clinicians, 17 staff) reported that many parents seemed receptive to discussing HPV vaccination at ages 9-10 years, pushback often stemmed from child expectations for a vaccine-free visit at age 9 years rather than vaccine concerns, and discussions at ages 9-10 years were shorter because sexual activity was not perceived as salient. Many preferred the option to space out vaccines by administering a single vaccine at age 9 years and fewer at age 11 years.

conclusionClinicians and staff perceived recommending the HPV vaccine at ages 9-10 years as feasible for clinicians, compatible with workflows, and generally acceptable to parents.

Indexed as

Attitude of Health PersonnelPapillomavirus InfectionsPapillomavirus VaccinesPatient Acceptance of Health CareCaliforniaChildColoradoFeasibility StudiesFemaleHumansMaleParentsPapillomavirus Vaccines

Identifiers

PMID40451241
PMCPMC13257910

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.