Evidence map›Paper›PMID 40451144›Full record

ArticleNeuroepidemiology2026

Self-Reported Dystonia and Dystonia on Neurological Examination: Prevalence and Concordance across Time in a Prospectively Followed Essential Tremor Cohort.

Tomer O Guy, Diane S Berry, Vibhash D Sharma, Elan D Louis

Abstract read
In one paragraph

Article in Neuroepidemiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Does the Severity of Arm Tremor in Essential Tremor Correlate with Impaired Balance?Tremor and other hyperkinetic movements (New York, N.Y.) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tomer O GuyDepartment of Neurology, University of Texas Southwestern Medical Center, Dallas, Texas, USA, tomer.guy@utsouthwestern.edu.
Diane S BerryDepartment of Neurology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Vibhash D SharmaDepartment of Neurology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Elan D LouisDepartment of Neurology, University of Texas Southwestern Medical Center, Dallas, Texas, USA, elan.louis@utsouthwestern.edu.

Funding

Clinical Pathological Study of Cognitive Impairment in Essential TremorR01NS086736 · NINDS · YALE UNIVERSITY · PI COSENTINO, STEPHANIE ANN, LOUIS, ELAN D · 2014 to 2023
$8.1M
NINDS NIH HHS R01 NS086736
6 · The paper itself

Abstract

<p>Introduction: Screening questions are important in identifying subgroups of individuals within a target population. Dystonic movements and postures are not uncommon in patients with essential tremor (ET). There is a gap in knowledge - no studies have assessed the validity of a self-report of dystonia in ET patients. We assessed the concordance between self-reported dystonia and the presence or absence of dystonia on examination (DOE).

methodsWe obtained self-report data from 274 ET cases in a serial study with up to five follow-up evaluations. At each assessment, participants could self-report dystonia, and they underwent a detailed neurological examination, from which a movement disorders neurologist assessed for the presence of DOE.

resultsAcross time, the prevalence of self-reported dystonia and DOE ranged from 0.0% to 4.3% and 8.6% to 17.5%, respectively. There were 74 cases with either self-reported dystonia or DOE; in only 3 (4.1%) was there a positive concordance between the two at each of their evaluations. Values for sensitivity ranged from 0.0% to 40%; specificity from 96.1% to 100%; positive predictive value from 0.0% to 67.0% (median 30.0%); and negative predictive value from 83.1% to 94.4%.

conclusionOur study provides important insights into the validity of self-report data on dystonia in ET and the prevalence of DOE in ET. Our findings suggest that self-reported dystonia was not a valid means to identify DOE in ET. </p>.

Indexed as

DystoniaEssential TremorNeurologic ExaminationSelf ReportAgedAged, 80 and overFemaleFollow-Up StudiesHumansMaleMiddle AgedPrevalenceProspective StudiesClinical settingCohortDystoniaEssential tremorProspective studyValidity

Identifiers

PMID40451144
PMCPMC12185053

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.