Evidence map›Paper›PMID 40450710›Full record

ArticleSmall (Weinheim an der Bergstrasse, Germany)2025

Polyglycerol-Grafted Graphene Oxide with pH-Responsive Charge-Convertible Surface to Dynamically Control the Nanobiointeractions for Enhanced in Vivo Tumor Internalization.

Yajuan Zou, Alberto Bianco, Yuta Nishina

Abstract read
In one paragraph

Article in Small (Weinheim an der Bergstrasse, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yajuan ZouResearch Institute for Interdisciplinary Science, Okayama University, 3-1-1 Tsushimanaka, Kita-ku, Okayama, 700 8530, Japan.ORCID 0000-0001-7178-3899
Alberto BiancoResearch Institute for Interdisciplinary Science, Okayama University, 3-1-1 Tsushimanaka, Kita-ku, Okayama, 700 8530, Japan.ORCID 0000-0002-1090-296X
Yuta NishinaResearch Institute for Interdisciplinary Science, Okayama University, 3-1-1 Tsushimanaka, Kita-ku, Okayama, 700 8530, Japan.ORCID 0000-0002-4958-1753

Funding

Centre National de la Recherche Scientifique MULTIDIMJSPS KAKENHI JP22H04548JSPS KAKENHI JP23K17213JST CREST JPMJCR20H3JST CREST JPMJCR24S6
6 · The paper itself

Abstract

pH-responsive charge-convertible nanomaterials (NMs) ameliorate the treatment of cancer via simultaneously reducing nonspecific interactions during systemic circulation and improving targeted uptake within solid tumors. While promising, little is known about how the pH-responsiveness of charge-convertible NMs directs their interactions with biological systems, leading to compromised performance, including off-target retention and low specificity to tumor cells. In the present study, polyglycerol-grafted graphene oxide bearing amino groups (GOPGNH

Indexed as

GlycerolGraphiteNeoplasmsPolymersAnimalsCell Line, TumorHumansHydrogen-Ion ConcentrationMaleic AnhydridesMiceSurface PropertiesGlycerolgraphene oxideGraphiteMaleic AnhydridespolyglycerolPolymerscharge conversionin vivo tumor internalizationnon‐specific interactionpH‐responsivenesspolyglycerol‐grafted graphene oxide

Identifiers

PMID40450710
PMCPMC12508724

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.