ArticleDiscover oncology2025
Global trends and characteristics of metal-organic frameworks in cancer research: a machine-learning-based bibliometric analysis.
Article in Discover oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Bibliometric and visualized analysis of metal‒organic frameworks in bone tissue engineering and bone diseases.Discover nano · 2026Review
- Progress in the Development of Metal-Organic Frameworks (MOFs) for Medical Imaging of Tumors: Prospects and Challenges.International journal of nanomedicine · 2026Review
- Global trends and knowledge structure of graphene based cancer research between 2016 and 2025.Discover oncology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
backgroundCancer poses a significant health threat, causing millions of deaths annually. Although chemotherapy-based comprehensive therapies are common, their low accuracy and severe side effects limit effectiveness. Metal-organic frameworks (MOFs), with their superior biocompatibility and stability, show great promise for drug delivery and cancer treatment. This study aims to explore the potential and developmental trajectories of MOFs in cancer research through a bibliometric analysis.
methodsThe Web of Science Core Collection was searched for documents from its inception in 2009 to December 31, 2023. We analyzed and visualized document types, countries, institutions, authors, journals, references, and keywords using the Bibliometrix package, dplyr, sankeywheel, term extraction, and ggplot2. Additionally, the Latent Dirichlet Allocation (LDA) algorithm was employed for detailed semantic analysis, uncovering latent thematic distributions.
resultsA total of 7106 authors from 1591 institutions across 45 countries contributed 1955 papers on MOFs in cancer research, published in 327 journals. China leads in research output and international collaboration, with the Chinese Academy of Sciences as the top institution. Lin Wenbin from the University of Chicago is the most influential author, and ACS Applied Materials & Interfaces is the most active journal. MOFs are predominantly studied for breast cancer, followed by lung and liver cancers. Drug delivery remains a focal point for future research.
conclusionsThis study provides a comprehensive overview of the research landscape on MOFs in cancer treatment, offering insights into key trends and future directions, particularly in drug delivery and disease-specific applications.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.