Evidence map›Paper›PMID 40450644›Full record

ArticleInternational urology and nephrology2025

Duplex ultrasound compared with digital subtraction angiography in diagnosing significant stenosis of vascular access.

Ali Jawas, Mohammad Murtuza, Fikri M Abu-Zidan

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in International urology and nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

3 authors.

Ali JawasDepartment of Surgery, College of Medicine and Health Sciences, United Arab Emirates University, Al-Ain, UAE. amjawas@yahoo.com.ORCID http://orcid.org/0000-0002-6413-9170
Mohammad MurtuzaDepartment of Radiology, Tawam Hospital, Al-Ain, UAE.
Fikri M Abu-ZidanThe Research Office, College of Medicine and Health Sciences, United Arab Emirates University, Al-Ain, UAE.ORCID http://orcid.org/0000-0003-0143-8568

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study evaluated the diagnostic accuracy of duplex ultrasound (DUS) using peak systolic velocity (PSV), PSV ratio (PSVR), and volume flow in detecting vascular access stenosis, compared to digital subtraction angiography.

methodsA cohort of 121 patients with arteriovenous (AV) fistulas or grafts were evaluated between January 2013 and September 2013 for clinical indicators of dysfunction, including reduced thrill, weak bruit, decreased dialysis flow, high venous pressure or excessive post-dialysis bleeding using our own collective diagnostic criteria based on previously published parameters. Critical stenosis was defined as PSV >400 cm/s, PSVR >3.5, and volume flow <400 mL/min. Angiography was performed for all hemodynamically significant stenoses diagnosed by DUS.

resultsAmong 121 patients (mean age, 56.6 ± 17.3 years; 64% men), DUS findings included normal studies (24%), mild stenosis (9.9%), moderate stenosis (15.7%), severe stenosis (40.5%), and total occlusions (9.9%). Stenosis locations were at the anastomotic site (86.3%), the junctional (11.3%), and the venous outflow (2.5%). Critical stenosis was identified in 49 (40.5%) patients. Of 46 patients who underwent angiography, critical stenosis was confirmed in 44. DUS demonstrated a positive predictive value (PPV) of 95.6% for detecting significant stenosis, supporting its reliability in vascular access assessment. Study limitations include its small sample size, retrospective design, and limited generalizability. Furthermore, analysis was limited to positive sonographic findings precluding sensitivity/specificity assessment.

conclusionDUS is accurate in diagnosing severe vascular access stenosis, with a PPV exceeding 95%. Its non-invasive nature and high predictive value support its use as a first-line imaging modality for vascular access evaluation.

Indexed as

Angiography, Digital SubtractionArteriovenous Shunt, SurgicalGraft Occlusion, VascularRenal DialysisUltrasonography, Doppler, DuplexAdultAgedBlood Flow VelocityConstriction, PathologicFemaleHumansMaleMiddle AgedRetrospective StudiesArteriovenous accessArteriovenous graftDuplex ultrasoundPatencyStenosis

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.