ArticleBMC global and public health2025
Effectiveness of a community health advisor colorectal cancer screening educational intervention on stool test completion in an African American primary care patient population: a pragmatic randomized controlled trial.
Article in BMC global and public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04304001 (Test Up Now Education Program), which is not on this map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Test Up Now Education Program
Who cites it
4 citing papers in PubMed.
- Monitoring of Colorectal Cancer Screening Adherence Among African American Patients of North Florida Community Health Centers.Journal of cancer education : the official journal of the American Association for Cancer Education · 2026Article
- Attitudes and beliefs regarding colorectal cancer screening among African American patients of community health centers in North-Central Florida and stakeholder perspectives: a qualitative study.BMC public health · 2026Article
- Mistrust and misinformation in a colorectal cancer care: rebuilding credibility in the digital age.Techniques in coloproctology · 2026Article
- Evidence on global public health cancer strategies.BMC global and public health · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
Abstract
backgroundColorectal cancer (CRC) disparities in incidence and mortality for African Americans compared to white Americans are explained by socioeconomic, behavioral, biological, and cultural factors in addition to lower screening rates and lower stage-specific survival. The behavioral clinical trial, "Test Up Now Education Program" (TUNE-UP) tested a community health advisor (CHA) intervention to increase stool-based screening in African American patients of community health centers (CHC) in Florida.
methodsParticipants who were not up to date with CRC screening were randomized to two study arms after completing a baseline survey. The two experimental arms were (1) an intervention group which received adapted "Screen to Save" CRC education, a tailored brochure, and CHA education; and (2) a control group which received the brochure only. Participants were surveyed at baseline, 3 months, and 12 months follow-up. The primary outcome was completion of the stool test within the last year, measured by self-report. The secondary outcomes were CRC knowledge, CRC perceived susceptibility, and CRC screening self-efficacy. For each arm, the proportion of participants who received CRC screening by 12 months was calculated. McNemar's chi-square test was used to test changes in dichotomous outcomes related to CRC screening. For outcome variables measured on a continuous scale, a paired t-test was applied to compare changes in mean values. Generalized estimating equations (GEE) models were used to compare effects of the intervention on secondary outcomes, adjusting for covariates and confounding factors.
resultsAt 12 months (n = 93), completion of the stool test increased significantly among participants in both study arms, showing no difference; 27 out of 45 (60%) participants in the intervention group and 28 out of 48 (58%) participants in the control group (p = 0.87).The intervention had a significant effect on the two secondary outcomes of CRC knowledge (p = 0.03) and CRC perceived susceptibility (p < 0.001) after adjusting for the covariates and confounders included in the model.
conclusionsThe trial demonstrated CHCs can increase CRC screening among African Americans who were not up to date in receiving recommended screening.
trial registrationThe clinical trial was registered on March 11, 2020 under the identifier https://clinicaltrials.gov/study/NCT04304001 .
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