Evidence map›Paper›PMID 40450259›Full record

ArticleBMC musculoskeletal disorders2025

Experimental study on the biomechanical loading of a four-dimensional plate for the fixation of femoral shaft fractures.

Meiling Song, Jian Wen, Zhe Wang, Yu Zeng, Jun Lu, Wei Lu, Changsheng Chen, Xieping Dong

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Article in BMC musculoskeletal disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Meiling SongJiangxi Provincial People's Hospital, The First Affiliated Hospital of Nanchang Medical College, JXHC Key Laboratory of Digital Orthopedics, Nanchang, 330006, China.
Jian WenJiangxi Provincial People's Hospital, The First Affiliated Hospital of Nanchang Medical College, JXHC Key Laboratory of Digital Orthopedics, Nanchang, 330006, China.
Zhe WangJiangxi Provincial People's Hospital, The First Affiliated Hospital of Nanchang Medical College, JXHC Key Laboratory of Digital Orthopedics, Nanchang, 330006, China.
Yu ZengJiangxi Provincial People's Hospital, The First Affiliated Hospital of Nanchang Medical College, JXHC Key Laboratory of Digital Orthopedics, Nanchang, 330006, China.
Jun LuSuzhou Kangli Orthopedics Instrument Co., Ltd., Suzhou, 215600, China.
Wei LuSuzhou Kangli Orthopedics Instrument Co., Ltd., Suzhou, 215600, China.
Changsheng ChenWuxi Times of Medical Science and Technology Co., Ltd., in Wuxi City, Jiangsu Province, 214187, China.
Xieping DongJiangxi Provincial People's Hospital, The First Affiliated Hospital of Nanchang Medical College, JXHC Key Laboratory of Digital Orthopedics, Nanchang, 330006, China. jxsrmyydongxieping@163.com.

Funding

The Jiangxi Province Technology Innovation Guidance Program Project 20212BDH81018The National Natural Science Foundation Regional Science Fund 8216090362The National Orthopedics and Sports Rehabilitation Clinical Medical Research Center Innovation Fund 2021-NCRC-CXJJ-PY-05
6 · The paper itself

Abstract

objectiveTo explore the biomechanical properties of a four-dimensional structure locking osteosynthesis plate that can alter its structure and functionality over time.

methodsAccording to the AO classification (AO-A2) standard, 18 artificial femoral shaft oblique fracture models with the same position and shape were generated and subsequently randomly divided into 2 groups (n = 9). In the experimental group, the four-dimensional locking plate was fixed, and in the control group, the locking plate was fixed. In vitro loading experiments were carried out under three conditions: 1400 N axial compression, 500 N internal and external four-point bending, and 15 N·m torsion. The average compression stiffness, average bending stiffness, average torsional stiffness, and displacement were compared between the two groups.

resultsUnder vertical loading, the average compression stiffness of the experimental group (558.7 ± 39.1) N/mm was greater than that of the control group (548.8 ± 24.5) N/mm, (P = 0.73); and the average displacement of the fracture end of the experimental group (3.3 ± 0.2) mm was lower than that of the control group (3.4 ± 0.3) mm, (P = 0.47). The differences were not statistically significant. Under four-point bending loading, the average bending stiffness of the experimental group (466.6 ± 85.8) N/mm was lower than that of the control group (542.5 ± 43.2) N/mm, and the difference was not statistically significant (P = 0.24). The average displacement of the fracture ends in the experimental group (1.6 ± 0.2)mm was greater than that in the control group (1.2 ± 0.1)mm, and the difference was statistically significant (P = 0.02). Under torsional loading, the average torsional stiffness of the experimental group (1.0 ± 0.1) N·m/deg was lower than that of the control group (1.1 ± 0.1) N·m/deg, (P = 0.27); and the average angular displacement of the fracture end of the experimental group (15.9 ± 1.3) deg was greater than that of the control group (14.6 ± 1.3) deg, (P = 0.26). There was no significant difference between the two groups.

conclusionThe anti-compression, anti-bending and anti-torsion properties of four-dimensional locking plates are similar to those of conventional locking plates and can meet the mechanical requirements of internal fracture fixation.

Indexed as

Bone PlatesFemoral FracturesFracture Fixation, InternalBiomechanical PhenomenaHumansMaterials TestingStress, MechanicalWeight-BearingA-BO fixationBiomechanical loadingFemoral stem fractureFour-dimensional structure locking plateInternal fixation

Identifiers

PMID40450259
PMCPMC12125866

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.