Trial reportBMC neurology2025
Effect of a nurse-led online patient support program on fatigue, sleep and quality of life in patients with multiple sclerosis: a quasi-experimental study.
Trial report in BMC neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06166043 (Evaluation of the Efficiency of the Nurse Follow-up Program Supported With Web Based Education in Managing Fatigue in Patient With Multiple Sclerosis), which is not on this map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of the Efficiency of the Nurse Follow-up Program Supported With Web Based Education in Managing Fatigue in Patient With Multiple Sclerosis
Who cites it
2 citing papers in PubMed.
- Nurse-Led Digital Interventions for Patients with Multiple Sclerosis: A Scoping Review.Medical sciences (Basel, Switzerland) · 2026Article
- Reconsidering Rehabilitation and Lifestyle Approaches to Improve Quality of Life in People with Multiple Sclerosis: A Scoping Review.Medicina (Kaunas, Lithuania) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMultiple sclerosis (MS) is becoming more prevalent. Physical impairments and sleep issues, particularly fatigue, diminish these patients' quality of life. One of the most successful and long-lasting strategies for managing symptoms is patient education. The aim of this study was to evaluate effect of a nurse-led online support program on fatigue, sleep, and quality of life in patients with multiple sclerosis (PwMS).
methodsThis quasi-experimental study was conducted in the MS outpatient clinic of a university hospital in Istanbul. Patients participated in a five-week nurse-led online support program and were assessed using the Fatigue Severity Scale (FSS), Pittsburgh Sleep Quality Index (PSQI), and EQ-5D Quality of Life Scale before, after, and at 3 and 6 months. Patients' step counts were also recorded.
resultsThirty patients who completed the program were included in the study. Compared to baseline, FSS scores and number of steps improved (p = 0.008, p = 0.008). PSQI scores also improved (p = 0.026). Although there was no difference in EQ-5D symptom scores, the EQ-5D visual analogue scale scores tended to improve (p = 0.085).
conclusionsA nurse-led online support program may be a feasible and resource-efficient approach to managing fatigue and sleep disturbances in PwMS, especially in settings with limited access to care. Larger controlled studies are needed to confirm these findings.
trial registrationThis study was registered on ClinicalTrials.gov on August 24, 2023 (NCT06166043).
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