Evidence map›Paper›PMID 40450174›Full record

ArticleScientific reports2025

A synbiotic improves performance and gut health in broiler chickens.

Ali Khosravi, Fatollah Boldaji, Behrouz Dastar, Mohammad Amir Karimi Torshizi, Morteza Alemi, Seyed Hossein Hoseinifar

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ali KhosraviDepartment of Animal and Poultry Nutrition, Faculty of Animal Science, Gorgan University of Agricultural Sciences and Natural Resources, Gorgan, 49189-4364, Iran. khosravi2006@gmail.com.
Fatollah BoldajiDepartment of Animal and Poultry Nutrition, Faculty of Animal Science, Gorgan University of Agricultural Sciences and Natural Resources, Gorgan, 49189-4364, Iran.
Behrouz DastarDepartment of Animal and Poultry Nutrition, Faculty of Animal Science, Gorgan University of Agricultural Sciences and Natural Resources, Gorgan, 49189-4364, Iran.
Mohammad Amir Karimi TorshiziDepartment of Poultry Nutrition, Tarbiat Modares University, Tehran, 14115-336, Iran.
Morteza AlemiDepartment of Animal and Poultry Physiology, Faculty of Animal Science, Gorgan University of Agricultural Sciences and Natural Resources, Gorgan, 49189-4364, Iran.
Seyed Hossein HoseinifarDepartment of Fisheries, Gorgan University of Agricultural Sciences and Natural resources, Gorgan, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Modulating the intestinal microbiota of birds by using probiotics and prebiotics to reduce mortality and increase poultry health is a method of interest in the poultry industry. This study aimed to determine the best combination of synbiosis between Enterococcus faecium and one of the four prebiotics: mannan oligosaccharide (MOS), oligofructose (OF), xylooligosaccharide (XOS) or galactooligosaccharide (GOS). Based on the results of laboratory studies, a synbiotic was selected for performance evaluation in broiler chickens. Based on the results of in vitro studies, E. faecium + GOS combination was selected for further study as a potential synbiotic. Four hundred broiler chickens of the Cobb 500 breed were randomly assigned to 4 experimental treatments, and each repetition had 20 birds of one-day-old chickens, males, and females. Experimental treatments included control, control + prebiotic GOS, control + E.faecium probiotic, and control + selected synbiotic. After six weeks of feeding, growth performance, immune response, and intestinal microbiota were evaluated. Administration of GOS and E.faecium as synbiotic positively affected performance, especially in the first periods of production (P < 0.05). Treatments containing synbiotic and prebiotic significantly reduced the population of E. coli compared to the control treatment (P < 0.05). These results showed that E.faecium + GOS can be an efficient synbiotic for broiler chickens. However, determining the selected synbiotic effects on challenged broiler chickens is a point of interest that merits further research.

Indexed as

ChickensGastrointestinal MicrobiomeSynbioticsAnimal FeedAnimalsEnterococcus faeciumFemaleMaleOligosaccharidesPrebioticsProbioticsoligofructoseOligosaccharidesPrebioticsBroiler chickensGrowth performanceIntestinal microbiotaPrebioticSynbiotic

Identifiers

PMID40450174
PMCPMC12126514

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.