ArticleScientific reports2025
Alleviating head-mounted weight burden for neural imaging in freely-behaving rodents.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- 2P-FENDO-II: A fiber bundle microscope for all-optical, large field-of-view brain studies in freely moving mice.Cell reports methods · 2026Article
Corrections and comments
- Erratum issued
- Update of
Authors and funding
5 authors.
Funding
Abstract
The recently developed miniaturized head-mounted two-photon (2P) imaging devices have served as a valuable tool for neuroscientists, enabling real-time functional neural imaging in freely-behaving animals. Although the current 2P fiberscopes and miniscopes are lightweight, the weight of any potential additional accessories inevitably imposes a burden on the animal. Here, we present a buoyancy levitation method to alleviate head-mounted weight burden on mice. By utilizing the buoyance of a helium-filled balloon to counteract the additional weight of up to 7 g, mice' motion behavior remains largely unaffected by the added load. Neuroimage analysis provides new insights into the effects of weight burden on neural activities. This easy-to-implement method offers a platform for studying neural network function in animals, effectively freeing them from the burden of head-mounted weight.
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Registered trials
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