Evidence map›Paper›PMID 40449506›Full record

ReviewThe Lancet. Oncology2025

National cancer control plans in Latin America and the Caribbean: challenges and future directions.

Cynthia Villarreal-Garza, Alejandro Aranda-Gutierrez, David G Gonzalez-Sanchez, Camila Bragança-Xavier, Gabriela Negrete-Tobar, Yanin Chavarri-Guerra, Alejandro Mohar, Carlos Barrios, Anelisa Coutinho, Ahmedin Jamal and 4 more

Erratum issuedAbstract readReview
In one paragraph

Review in The Lancet. Oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. [2018-2024 Cancer Trends in Pathology of a Hospital in Eastern Mexico].Revista medica del Instituto Mexicano del Seguro Social · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Cynthia Villarreal-GarzaBreast Cancer Center, Hospital Zambrano Hellion, Tecnologico de Monterrey, San Pedro Garza Garcia, Mexico.
Alejandro Aranda-GutierrezDepartamento de Hemato-Oncología, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
David G Gonzalez-SanchezUniversity of Missouri-Kansas City School of Medicine, Kansas City, MO, USA.
Camila Bragança-XavierDepartment of Clinical Oncology, Hospital Sirio-Libanês, São Paulo, Brazil.
Gabriela Negrete-TobarCentro Javeriano de Oncología, Hospital Universitario San Ignacio, Bogotá, Colombia.
Yanin Chavarri-GuerraDepartamento de Hemato-Oncología, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
Alejandro MoharUnidad de Epidemiología e Investigación Biomédica en Cáncer, Instituto de Investigaciones Biomédicas, UNAM-Instituto Nacional de Cancerología, Mexico City, Mexico.
Carlos BarriosLatin American Cooperative Oncology Group (LACOG), Porto Alegre, Brazil.
Anelisa CoutinhoBrazilian Society of Clinical Oncology (SBOC), Salvador, Brazil.
Ahmedin JamalAmerican Cancer Society, Atlanta, GA, USA.
Hedvig HricakDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Molecular Pharmacology Program, Sloan Kettering Institute, New York, NY, USA; Department of Radiology, Weill Cornell Medical College, New York, NY, USA; Gerstner Sloan Kettering Graduate School of Biomedical Sciences, New York, NY, USA.
Patrick LoehrerIndiana University School of Medicine, Indianapolis, IN, USA.
Fabio Ynoe MoraesDepartment of Oncology, Queen's University, Kingston, ON, Canada.
Raúl MurilloCentro Javeriano de Oncología, Hospital Universitario San Ignacio, Bogotá, Colombia; Faculty of Medicine, Pontificia Universidad Javeriana, Bogota, Colombia. Electronic address: rmurillo@husi.org.co.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Tumor Microenvironment and Metastasis ProgramP30CA082709 · NCI · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI Sara K Quinney · 1999 to 2026
$59.3M
NCI NIH HHS P30 CA008748NCI NIH HHS P30 CA082709
6 · The paper itself

Abstract

In this Policy Review, we examine cancer incidence and mortality rates across Latin America and the Caribbean, focusing on national cancer control plans (NCCPs) as frameworks for reducing the cancer burden in the region. By 2022, only 16 countries had active NCCPs, with eight being cancer specific and eight being integrated into public health plans. Our analysis found that dedicated NCCPs were linked to reduced cancer incidence but not reduced mortality. Broader socioeconomic indicators, such as universal health coverage and a higher Human Development Index, were more strongly associated with improved cancer outcomes, including reduced mortality-to-incidence ratios. Prevention measures such as cervical cancer screening and compliance with WHO's MPOWER tobacco control strategies also reduced cancer incidence, underscoring the importance of public health policies. However, challenges including insufficient cancer registries, underfunding, and health-care inequities hinder NCCP implementation. Addressing these gaps requires sustainable registries, regional evaluation frameworks, global collaboration, and stronger political commitment to ensure the success of NCCPs.

Indexed as

Health PolicyNeoplasmsCaribbean RegionEarly Detection of CancerHealthcare DisparitiesHumansIncidenceLatin America

Identifiers

PMID40449506
PMCPMC12418520

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.