Evidence map›Paper›PMID 40449254›Full record

ArticleJournal of biomechanics2025

Four-dimensional computed tomography-derived distal radioulnar joint osteokinematics during pronosupination with unilateral triangular fibrocartilage complex injuries.

Taylor P Trentadue, Cesar Lopez, Andrew Thoreson, Robert A Foley, Nikkole M Weber, David R Holmes, Kai-Nan An, Shuai Leng, Kristin D Zhao, Sanjeev Kakar

Abstract read
In one paragraph

Article in Journal of biomechanics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Taylor P TrentadueAssistive and Restorative Technology Laboratory, Rehabilitation Medicine Research Center, Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN, USA; Mayo Clinic Medical Scientist Training Program, Mayo Clinic, Rochester, MN, USA; Mayo Clinic Graduate Program in Biomedical Engineering and Physiology, Mayo Clinic, Rochester, MN, USA. Electronic address: trentadue.taylor@mayo.edu.
Cesar LopezAssistive and Restorative Technology Laboratory, Rehabilitation Medicine Research Center, Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN, USA. Electronic address: lopez.cesar@mayo.edu.
Andrew ThoresonAssistive and Restorative Technology Laboratory, Rehabilitation Medicine Research Center, Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN, USA. Electronic address: thoreson.andrew@mayo.edu.
Robert A FoleyAssistive and Restorative Technology Laboratory, Rehabilitation Medicine Research Center, Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN, USA. Electronic address: robert.a.foley@und.edu.
Nikkole M WeberComputed Tomography Clinical Innovation Center, Mayo Clinic, Rochester, MN, USA; Department of Radiology, Mayo Clinic, Rochester, MN, USA. Electronic address: weber.nikkole@mayo.edu.
David R HolmesDepartment of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA; Biomedical Imaging Resource Core Facility, Mayo Clinic, Rochester, MN, USA. Electronic address: holmes.david3@mayo.edu.
Kai-Nan AnAssistive and Restorative Technology Laboratory, Rehabilitation Medicine Research Center, Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN, USA; Medical Device Innovation Center, National Cheng Kung University, Tainan, Taiwan. Electronic address: an.kainan@mayo.edu.
Shuai LengComputed Tomography Clinical Innovation Center, Mayo Clinic, Rochester, MN, USA; Department of Radiology, Mayo Clinic, Rochester, MN, USA; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA. Electronic address: leng.shuai@mayo.edu.
Kristin D ZhaoAssistive and Restorative Technology Laboratory, Rehabilitation Medicine Research Center, Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN, USA; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA. Electronic address: zhao.kristin@mayo.edu.
Sanjeev KakarDivision of Hand and Upper Extremity Surgery, Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA. Electronic address: kakar.sanjeev@mayo.edu.

Funding

Musculoskeletal Research Training ProgramT32AR056950 · NIAMS · MAYO CLINIC ROCHESTER · PI Jennifer J Westendorf · 2009 to 2026
$7.0M
Medical Scientist Traning Program at Mayo ClinicT32GM065841 · NIGMS · MAYO CLINIC ROCHESTER · PI KAUFMANN, SCOTT H, SCHIMMENTI, LISA A · 2003 to 2022
$5.8M
MSTP at Mayo Clinic RochesterT32GM145408 · NIGMS · MAYO CLINIC ROCHESTER · PI SCOTT H KAUFMANN, LISA A SCHIMMENTI · 2023 to 2026
$4.7M
Toward use of the synergy-based SoftHand Pro for activities of daily living by transradial amputees: A multi-site clinical trialR01HD102615 · NICHD · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI SANTELLO, MARCO, ZHAO, KRISTIN DAIGLE · 2021 to 2025
$3.1M
Comprehensive characterization of coronary atherosclerotic disease using photon-counting-detector dual-source CT and its impact on patient managementR01EB028590 · NIBIB · MAYO CLINIC ROCHESTER · PI LENG, SHUAI, MCCOLLOUGH, CYNTHIA H · 2020 to 2023
$2.6M
4D CT Imaging for Improved Diagnosis and Treatment of Wrist Ligament InjuriesR01AR071338 · NIAMS · MAYO CLINIC ROCHESTER · PI ZHAO, KRISTIN DAIGLE · 2017 to 2021
$2.2M
Assessing scaphotrapeziotrapezoid arthrokinematics using 4DCTF31AR082227 · NIAMS · MAYO CLINIC ROCHESTER · PI TRENTADUE, TAYLOR PATRICIA · 2023 to 2025
$116k
NIAMS NIH HHS F31 AR082227NIAMS NIH HHS R01 AR071338NIAMS NIH HHS T32 AR056950NIBIB NIH HHS R01 EB028590NICHD NIH HHS R01 HD102615NIGMS NIH HHS T32 GM065841NIGMS NIH HHS T32 GM145408
6 · The paper itself

Abstract

The distal radioulnar joint (DRUJ) is a load-bearing joint that permits pronosupination of the forearm. Pronosupination may provoke instability following injuries to the soft tissue stabilizers of the joint, particularly when loaded against resistance. The objective of this study was to assess osteokinematics between the radius and ulna during pronosupination in 12 participants with suspected unilateral DRUJ injury enrolled in a prospective study using four-dimensional computed tomography (4DCT) at baseline and six months after arthroscopic surgery. We hypothesized that inter-landmark distances between the ulnar styloid and three landmarks on the distal radius-the central reference point, dorsal corner, and volar corner-would be related to relative pronosupination position, wrist injury status (injured versus uninjured), application of load (unresisted versus resisted), and timepoint (preoperative versus postoperative). Generalized linear mixed effects models were created to assess the change in inter-landmark distances with different levels of the predictor variables. Inter-landmark distances at all three radius landmarks were significantly associated with pronosupination angle and application of resistance. The effects of injury and surgery were less consistent and, if present, significant at only the volar corner landmark. The random effect for participant was statistically significant in all models. 4DCT-derived osteokinematics reflect position in the pronosupination arc and the application of resistance. However, the effect of injury or intervention was not statistically significant in the majority of single-landmark models. This suggests that 4DCT detects changes in biomechanical phenomena, although more sophisticated biomarkers may be justified for injury classification.

Indexed as

Four-Dimensional Computed TomographyPronationRadiusTriangular FibrocartilageWrist InjuriesWrist JointAdultFemaleHumansMaleMiddle AgedProspective StudiesUlnaYoung AdultDistal radioulnar jointDynamic computed tomographyFour-dimensional computed tomographyPhoton-counting detector computed tomographyWrist biomechanics

Identifiers

PMID40449254
PMCPMC12338496

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.