ArticlePsychiatry research2025
Investigating the familiality of trichotillomania and excoriation disorder.
Article in Psychiatry research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- A genomic study of trichotillomania and excoriation disorder in families.Translational psychiatry · 2026Article
- Shame among parents of children with trichotillomania: influencing factors and management strategies.BMC psychiatry · 2026Article
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Authors and funding
7 authors.
Funding
Abstract
Trichotillomania (TTM) and excoriation disorder (ED) run in families and are thought to have shared etiological underpinnings. Only a few small studies have compared the family history of individuals with TTM, ED, and both conditions. To better understand shared predispositions, we examined self-reported family history of mental health disorders using cross-sectional survey responses from a genetics study of probands ages 4-66 years with TTM only (n = 69), ED only (n = 34), and both conditions (n = 70). Individuals with TTM only reported higher rates of having a first-degree relative with TTM (25 %, 17/69) compared to individuals with ED only (6 %, 2/34) (p = 0.03). Those with ED only reported higher rates of a first-degree relative with ED (41 %, 14/34) compared to individuals with TTM only (13 %, 9/69) (p = 0.002). Individuals with both conditions reported high rates of first-degree relatives with TTM (21 %, 15/70) and ED (39 %, 27/70). All three groups reported high rates of family history of anxiety (48 %-59 %), depression (41 %-49 %), ADHD (23 %-31 %), and OCD (17 %-18 %). Comparing mental health history in parents, there were no significant differences between the parents for TTM or ED, but mothers had higher rates than fathers of anxiety (42 % maternal vs. 18 % paternal) and depression (34 % maternal vs. 14 % paternal) (p-values < 0.001). Our results provide evidence of both shared and distinct predispositions between TTM and ED, highlighting the need for further research on genetic and environmental factors contributing to these conditions.
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