ArticlePediatric surgery international2025
Comments on the "Risk factors of bowel perforation in neonates with Hirschsprung disease".
Article in Pediatric surgery international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
This letter discusses methodological concerns regarding the diagnosis of pneumatosis intestinalis (PI) as an independent risk factor for bowel perforation in neonates with Hirschsprung's disease (HSCR), as presented in the study by Liu et al. (2025). The author highlights the lack of clear radiological criteria for PI diagnosis, noting that nonspecific findings (e.g., dilated bowel loops) were used without quantitative thresholds or inter-observer validation. The letter emphasizes the need for standardized diagnostic criteria, independent radiological reviews, and histopathological correlation to strengthen the study's reliability. These refinements would enhance the clinical applicability of the findings and support more accurate risk stratification for perforation in HSCR patients.
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